Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
interferon gamma
Summary
- Gene Symbol
-
- IFNG
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Antiviral defense
- Cleavage on pair of basic residues
- Cytokine
- Direct protein sequencing
- Glycoprotein
- Growth regulation
- Pharmaceutical
- Pyrrolidone carboxylic acid
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A7R8GUN6 |
|
| P01579 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| microglial cell activation | ||
| microglial cell activation | ||
| positive regulation of cytokine production | ||
| adaptive immune response |
GO Hierarchy
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of cellular respiration
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of cellular respiration
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of cellular respiration
- positive regulation of cell population proliferation
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of cellular respiration
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of cellular respiration
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of cell population proliferation
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of cellular respiration
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
positive regulation of alpha-beta T cell activation [inference]
regulation of alpha-beta T cell differentiation [inference]
regulation of CD4-positive, alpha-beta T cell activation [inference]
positive regulation of T cell activation [inference]
positive regulation of lymphocyte activation [inference]
regulation of immune response [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
regulation of metabolic process
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of protein metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular catabolic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of nucleotide metabolic process [inference]
regulation of phosphorylation [inference]
positive regulation of phosphate metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of protein metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of cellular localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of protein metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cell differentiation [inference]
positive regulation of cell adhesion [inference]
positive regulation of cell activation [inference]
positive regulation of response to stimulus [inference]
positive regulation of transport [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production
positive regulation of cell activation [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
positive regulation of cell differentiation [inference]
regulation of cell development [inference]
positive regulation of cell development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell adhesion [inference]
regulation of cell-cell adhesion [inference]
positive regulation of cell-cell adhesion [inference]
regulation of leukocyte cell-cell adhesion [inference]
positive regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
regulation of cellular catabolic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of nucleotide metabolic process [inference]
regulation of phosphorylation [inference]
positive regulation of phosphate metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of cell differentiation [inference]
positive regulation of cell differentiation [inference]
regulation of cell development [inference]
positive regulation of cell development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cell differentiation [inference]
positive regulation of cell adhesion [inference]
positive regulation of cell activation [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
positive regulation of alpha-beta T cell activation [inference]
regulation of alpha-beta T cell differentiation [inference]
regulation of CD4-positive, alpha-beta T cell activation [inference]
positive regulation of T cell activation [inference]
positive regulation of lymphocyte activation [inference]
positive regulation of cell activation [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
positive regulation of alpha-beta T cell activation [inference]
regulation of alpha-beta T cell differentiation [inference]
regulation of CD4-positive, alpha-beta T cell activation [inference]
positive regulation of T cell activation [inference]
positive regulation of lymphocyte activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production
positive regulation of cell activation [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
regulation of leukocyte differentiation [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular space | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine activity | ||
| cytokine activity | ||
| cytokine activity | ||
| type II interferon receptor binding | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Interferon gamma
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| adaptive immune response |
| cytokine activity |
| defense response to virus |
| humoral immune response |
| immune response |
| type II interferon receptor binding |
| InterPro |
|---|
| Four-helical cytokine-like, core |
| Interferon gamma |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080162 | lupus nephritis | |
| DOID:0080325 | tuberous sclerosis 2 | |
| DOID:0081267 | graft-versus-host disease | |
| DOID:0112006 | immunodeficiency 69 | |
| DOID:10003 | sensorineural hearing loss | |
| DOID:12134 | factor VIII deficiency | |
| DOID:12306 | vitiligo | |
| DOID:12361 | Graves' disease | |
| DOID:12449 | aplastic anemia | |
| DOID:12704 | ataxia telangiectasia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3458 | Xenbase:XB-GENE-17334391 | ||
| 15978 | ZFIN:ZDB-GENE-040629-1 | MOUSE00188 | |
| 25712 | ZFIN:ZDB-GENE-040629-1 | RATNO37895 | |
| 281237 | BOVIN29466 | ||
| 396991 | PIGXX25778 | ||
| 403801 | CANLF01400 | ||
| 443396 | SHEEP14465 | ||
| 449517 | PANTR06336 | ||
| 493965 | FELCA16987 | ||
| 574282 | MACMU03702 |
