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G protein subunit alpha transducin 3

Summary

Gene Symbol

GNAT3

Organism

Homo sapiens (human)

External Links

NCBI Gene

346562

PubChem

346562

Alliance of Genome Resources

HGNC:22800

Annotation

Keyword

Cytoplasm
GTP-binding
Magnesium
Metal-binding
Myristate
Proteomics identification
Reference proteome
Transducer

Proteins

Displaying 1 entry
UniProt	Protein Name
A8MTJ3	Gustducin alpha-3 chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
detection of chemical stimulus involved in sensory perception of bitter taste	IBA
sensory perception of sweet taste	IBA
sensory perception of umami taste	IEA
response to nicotine	IEA
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste [inference]

response to stimulus [inference]

response to chemical [inference]

response to nicotine

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of bitter taste

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of taste [inference]

detection of chemical stimulus involved in sensory perception of bitter taste

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protein-containing complex	IDA
apical plasma membrane	IEA
plasma membrane	TAS
photoreceptor outer segment	IBA
photoreceptor inner segment	IBA

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

heterotrimeric G-protein complex

catalytic complex [inference]

GTPase complex [inference]

heterotrimeric G-protein complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

Displaying **all 5** entries
GO Term	Evidence Code	PMID
G-protein beta/gamma-subunit complex binding	IBA
GTPase activity	IBA
G protein-coupled receptor binding	IBA
metal ion binding	IEA
GTP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

G-protein beta/gamma-subunit complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha subunit

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
G protein-coupled receptor binding
G-protein beta/gamma-subunit complex binding
GTP binding
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
guanyl nucleotide binding
nucleotide binding

Displaying **all 3** entries
InterPro
G protein alpha subunit, helical insertion
Guanine nucleotide binding protein (G-protein), alpha subunit
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1858	McCune Albright syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 63 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	171675		WB:WBGene00001678
Caenorhabditis elegans	176865		WB:WBGene00001666
Mus musculus	242851		MGI:3588268	MOUSE44812
Rattus norvegicus	286924		RGD:727817	RATNO29772
Pan troglodytes	472426	9598_0:001fb1		PANTR40623
Canis lupus familiaris	491406			CANLF05574
Bos taurus	516262			BOVIN27861
Macaca mulatta	708828			MACMU32373
Saccharomyces cerevisiae S288C	856394		SGD:S000001047
Monodelphis domestica	100012963			MONDO33494

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OrthoDB (Group)

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Acknowledgements