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Standards Ontologies Notations
L-2-hydroxyglutarate dehydrogenase

Summary
Gene Symbol
  • L2HGDH
Organism
Drosophila melanogaster (fruit fly)
NCBI Gene
35156
KEGG Gene ID
dme:Dmel_CG10639
PubChem
35156
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • FAD
  • Nucleotide-binding
  • Oxidoreductase
  • Proteomics identification
  • Reference proteome
Proteins
Displaying 1 entry
UniProt Protein Name
Q9VJ28
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
dehydrogenase
Functional Category
  • E: Amino acid transport and metabolism
  • I: Lipid transport and metabolism
  • T: Signal transduction mechanisms
Displaying 1 entry
Gene Ontology
oxidoreductase activity
Displaying all 2 entries
InterPro
FAD dependent oxidoreductase
FAD/NAD(P)-binding domain superfamily
Alliance of Genome Resources
Expression
Displaying 1 entry
Location References
Rhea

RHEA:21252

A + (S)-2-hydroxyglutarate
2-oxoglutarate + AH2
Enzyme
PMID
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:0050573 2-hydroxyglutaric aciduria
DOID:0050574 L-2-hydroxyglutaric aciduria
DOID:0050753 cerebellar ataxia
DOID:11832 visual epilepsy
DOID:2476 hereditary spastic paraplegia
Ortholog
Displaying entries 1 - 10 of 43 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
79944 HGNC:20499
178733 WB:WBGene00021564
217666 MGI:2384968
314196 RGD:1306250
566872 ZFIN:ZDB-GENE-090319-6
4816926 7237_1:001ab5
6497466 7217_1:0029ae
6529640 7245_1:001864
6549344 7220_1:002956
6561783 7222_1:000dcb
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024