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MIRAGE
recombination signal binding protein for immunoglobulin kappa J region
Summary
- Gene Symbol
-
- RBPJ
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative splicing
- Cytoplasm
- DNA-binding
- Disease variant
- Host-virus interaction
- Notch signaling pathway
- Nucleus
- Reference proteome
- Repeat
- Repressor
- Transcription regulation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q06330 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| angiogenesis | ||
| somitogenesis | ||
| epithelial to mesenchymal transition |
GO Hierarchy
- regulation of generation of precursor metabolites and energy
- regulation of generation of precursor metabolites and energy
biological process
cellular process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| chromatin | ||
| MAML1-RBP-Jkappa- ICN1 complex | ||
| MAML1-RBP-Jkappa- ICN1 complex | ||
| nucleus | ||
| nucleoplasm |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- recombining binding protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060227 | Adams-Oliver syndrome | |
| DOID:12930 | dilated cardiomyopathy |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3516 | Xenbase:XB-GENE-490756 | ||
| 19664 | MOUSE45791 | ||
| 445779 | CIOIN04885 | ||
| 461152 | PANTR33450 | ||
| 479122 | CANLF12284 | ||
| 563306 | DANRE41366 | ||
| 679028 | RATNO08881 | ||
| 694601 | MACMU36776 | ||
| 767928 | BOVIN31317 | ||
| 100083614 | ORNAN09935 |
