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Poly [ADP-ribose] polymerase 2

Summary

Gene Symbol

parp-2

Organism

Caenorhabditis elegans

External Links

NCBI Gene

3565967

PubChem

3565967

Alliance of Genome Resources

WB:WBGene00004050

Annotation

Keyword

DNA repair
Glycosyltransferase
NAD
Nucleotidyltransferase
Nucleus
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q09525	Poly ADP-ribose metabolism enzyme 2 Protein poly-ADP-ribosyltransferase parp-2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein poly-ADP-ribosylation	IBA IDA	12145714 15923155
cellular response to DNA damage stimulus	IEA
DNA repair	IEA
double-strand break repair	IBA
DNA damage response	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein poly-ADP-ribosylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein poly-ADP-ribosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein poly-ADP-ribosylation

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein poly-ADP-ribosylation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein poly-ADP-ribosylation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

double-strand break repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response

DNA repair

double-strand break repair

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response

DNA repair

double-strand break repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response

DNA repair

double-strand break repair

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nucleus	IEA
nucleolus	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
NAD+ ADP-ribosyltransferase activity	IBA IDA IEA	12145714 15923155
glycosyltransferase activity	IEA
transferase activity	IEA
NAD+-protein ADP-ribosyltransferase activity	IBA
nucleotidyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

pentosyltransferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

catalytic activity, acting on a protein [inference]

NAD+-protein ADP-ribosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Danio rerio	100007906	ZFIN:ZDB-GENE-031113-6
Xenopus tropicalis	100145803	Xenbase:XB-GENE-987109
Xenopus tropicalis	100495846	Xenbase:XB-GENE-1001702
Homo sapiens	10038	HGNC:272
Mus musculus	11546	MGI:1341112
Rattus norvegicus	290027	RGD:1310568