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aquaporin 2
Summary
- Gene Symbol
-
- AQP2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Diabetes insipidus
- Disease variant
- Glycoprotein
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P41181 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| renal water homeostasis | ||
| renal water homeostasis | ||
| renal water transport | ||
| water transport | ||
| water transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| water transmembrane transporter activity | ||
| protein binding | ||
| glycerol transmembrane transporter activity | ||
| water channel activity | ||
| water channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Aquaporin
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| water channel activity |
| InterPro |
|---|
| Aquaporin transporter |
| Aquaporin-like |
| Major intrinsic protein, conserved site |
| Major intrinsic protein |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081061 | nephrogenic diabetes insipidus type 2 | |
| DOID:12387 | nephrogenic diabetes insipidus |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 358 | SGD:S000006396 | ||
| 359 | Xenbase:XB-GENE-481401 | ||
| 361 | SGD:S000006396 | ||
| 362 | SGD:S000006396 | ||
| 11826 | SGD:S000006396 | ||
| 11827 | Xenbase:XB-GENE-481401 | MOUSE16374 | |
| 11829 | SGD:S000006396 | ||
| 11830 | SGD:S000006396 | ||
| 11831 | SGD:S000006396 | ||
| 25240 | SGD:S000006396 |
