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wunen

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

35966

PubChem

35966

Alliance of Genome Resources

FB:FBgn0016078

Annotation

Keyword

Alternative splicing
Developmental protein
Glycoprotein
Hydrolase
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9V576	Germ cell guidance factor Phosphatidic acid phosphatase type 2 Protein wunen
A0A0B4K7K7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
open tracheal system development	IMP	22675212
germ cell migration	IEP IMP TAS	12372264 16301333 8985246 9637912 9988212
eggshell formation	IMP	37508432
defense response to Gram-negative bacterium	HMP	19520911
septate junction assembly	IMP	22675212

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

dephosphorylation [inference]

phospholipid dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

lipid modification [inference]

phospholipid dephosphorylation

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process

lipid modification [inference]

phospholipid dephosphorylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process

lipid modification [inference]

phospholipid dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular process [inference]

signal transduction

cell death [inference]

programmed cell death [inference]

programmed cell death involved in cell development [inference]

ectopic germ cell programmed cell death

cellular process involved in reproduction in multicellular organism [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

dephosphorylation [inference]

phospholipid dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

lipid modification [inference]

phospholipid dephosphorylation

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

ectopic germ cell programmed cell death

cell motility [inference]

cell migration [inference]

germ cell migration

cell chemotaxis [inference]

germ cell repulsion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

septate junction assembly

tight junction organization [inference]

tight junction assembly [inference]

septate junction assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

cellular process involved in reproduction in multicellular organism [inference]

developmental process [inference]

developmental process involved in reproduction [inference]

anatomical structure formation involved in morphogenesis [inference]

eggshell formation

anatomical structure development [inference]

system development [inference]

respiratory system development [inference]

open tracheal system development

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

ectopic germ cell programmed cell death

locomotion [inference]

taxis [inference]

chemotaxis [inference]

negative chemotaxis [inference]

germ cell repulsion

cell chemotaxis [inference]

germ cell repulsion

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of defense response [inference]

negative regulation of innate immune response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of defense response [inference]

negative regulation of innate immune response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of cellular process [inference]

signal transduction

Displaying **all 4** entries
GO Term	Evidence Code	PMID
lateral plasma membrane	IDA	37508432
septate junction	IDA	22675212
plasma membrane	IBA
apical part of cell	IDA	22675212 37508432

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

lateral plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

septate junction

apical part of cell

Displaying **all 2** entries
GO Term	Evidence Code	PMID
phosphatase activity	IDA	12856002
phosphatidate phosphatase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

lipid phosphatase activity [inference]

phosphatidate phosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Lipid phosphate phosphohydrolase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
phospholipid dephosphorylation
phospholipid metabolic process

Displaying **all 3** entries
InterPro
Phosphatidate (PA) phosphatase-related
Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
Phosphatidic acid phosphatase type 2/haloperoxidase

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
lateral plasma membrane	PMID:37508432
apical part of cell	PMID:22675212 PMID:37508432
septate junction	PMID:22675212
membrane	FB:FBrf0231198

Rhea

RHEA:27429

H₂O + a 1,2-diacyl-sn-glycero-3-phosphate

a 1,2-diacyl-sn-glycerol + phosphate

Enzyme

3.1.3.4

PMID

RHEA:36239

H₂O + 1-O-alkyl-2-acyl-sn-glycero-3-phosphate

phosphate + 1-O-alkyl-2-acyl-sn-glycerol

Enzyme

3.1.3.4

Ortholog

Displaying entries **41 - 50** of 55 in total

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Species	Gene ID	OrthoDB
Drosophila navojoa	108654978	7232_1:001d5a
Drosophila serrata	110176841	7274_0:000c89
Drosophila obscura	111076119	7282_0:000b49
Drosophila hydei	111599924	7224_1:0019e6
Drosophila novamexicana	115762041	47314_0:001775
Drosophila mauritiana	117136460	7226_1:000a1f
Drosophila miranda	117193177	7229_1:004700
Drosophila albomicans	117569591	7291_1:0021ff
Drosophila guanche	117591097	7266_1:00077b
Drosophila innubila	117783126	198719_1:000d68