pancreatic and duodenal homeobox 1

Summary
Gene Symbol
  • PDX1
Organism
Homo sapiens (human)
NCBI Gene
3651
PubChem
3651
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Activator
  • Cytoplasm
  • DNA-binding
  • Developmental protein
  • Diabetes mellitus
  • Disease variant
  • Homeobox
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Transcription regulation
Proteins
Displaying 1 entry
UniProt Protein Name
P52945
  • Glucose-sensitive factor
  • Insulin promoter factor 1
  • Insulin upstream factor 1
  • Islet/duodenum homeobox-1
  • Somatostatin-transactivating factor 1
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
homeobox
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • K: Transcription
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying entries 1 - 10 of 12 in total
DO ID Disease Name Source
DOID:0050524 maturity-onset diabetes of the young
DOID:0050877 pancreatic agenesis
DOID:0080998 acute necrotizing pancreatitis
DOID:0111103 maturity-onset diabetes of the young type 4
DOID:3526 cerebral infarction
DOID:3891 placental insufficiency
DOID:4195 hyperglycemia
DOID:8947 diabetic retinopathy
DOID:9351 diabetes mellitus
DOID:9352 type 2 diabetes mellitus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024