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Cyclic nucleotide-gated ion channel subunit A

Summary

Gene Symbol

CngA

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

36806

PubChem

36806

Alliance of Genome Resources

FB:FBgn0261612

Annotation

Keyword

Coiled coil
Glycoprotein
Ligand-gated ion channel
Reference proteome
Transmembrane helix
cGMP-binding

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q24278	Cyclic nucleotide-gated ion channel subunit A
A0A0B4JCU4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
monoatomic cation transmembrane transport	IBA IDA	7957070 9512030 9878057
response to hypoxia	IGI IMP	20592263
transmembrane transport	IEA
monoatomic ion transport	IEA
ion transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic cation transport [inference]

monoatomic cation transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA
plasma membrane	IBA
intracellular cyclic nucleotide activated cation channel complex	IBA IDA NAS	11208535 7957070 9512030 9878057

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

intracellular cyclic nucleotide activated cation channel complex

cellular anatomical entity [inference]

membrane

plasma membrane

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GO Term	Evidence Code	PMID
intracellular cyclic nucleotide-activated monoatomic cation channel activity	IDA	7957070 9512030 9878057
protein-containing complex binding	IBA
intracellular cGMP-activated cation channel activity	IBA
ion channel activity	IEA
monoatomic ion channel activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity [inference]

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity [inference]

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

intracellular ligand-gated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

cyclic nucleotide-activated monoatomic ion channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

ligand-gated monoatomic cation channel activity [inference]

intracellular cyclic nucleotide-activated monoatomic cation channel activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

cGMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

ion binding [inference]

anion binding [inference]

cGMP binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

cyclic nucleotide binding [inference]

cGMP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

cGMP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cyclic nucleotide-gated cation channel

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
monoatomic ion channel activity
monoatomic ion transport

Displaying **all 4** entries
InterPro
Cyclic nucleotide-binding domain superfamily
Cyclic nucleotide-binding domain
Ion transport domain
RmlC-like jelly roll fold

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
intracellular cyclic nucleotide activated cation channel complex	PMID:7957070 PMID:9512030 PMID:9878057

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0110007	achromatopsia 2	Alliance of Genome Resources
DOID:0110377	retinitis pigmentosa 49	Alliance of Genome Resources
DOID:10584	retinitis pigmentosa	Alliance of Genome Resources
DOID:13399	color blindness	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 60 in total

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Species	Gene ID	Alliance of Genome Resources
Homo sapiens	1259	HGNC:2148
Homo sapiens	1260	HGNC:2149
Homo sapiens	1261	HGNC:2150
Homo sapiens	1262	HGNC:2152
Mus musculus	12788	MGI:88436
Mus musculus	12789	MGI:108040
Mus musculus	12790	MGI:1341818
Rattus norvegicus	25411	RGD:2367
Rattus norvegicus	85257	RGD:70948
Rattus norvegicus	85258	RGD:619844