GlyCosmos Portal

Submissions

integrin subunit alpha M

Summary

Gene Symbol

ITGAM

Organism

Homo sapiens (human)

External Links

NCBI Gene

3684

PubChem

3684

Alliance of Genome Resources

HGNC:6149

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Cell adhesion
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Innate immunity
Integrin
Magnesium
Metal-binding
Receptor
Reference proteome
Repeat
Signal
Systemic lupus erythematosus
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P11215	CD11 antigen-like family member B CR-3 alpha chain Cell surface glycoprotein MAC-1 subunit alpha Leukocyte adhesion receptor MO1 Neutrophil adherence receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
complement receptor mediated signaling pathway	ISS
positive regulation of microglial cell mediated cytotoxicity	ISS
positive regulation of neutrophil degranulation	IGI	21193407
receptor-mediated endocytosis	ISS
positive regulation of prostaglandin-E synthase activity	ISS

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response [inference]

innate immune response

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

cell adhesion

cell-substrate adhesion [inference]

cell-matrix adhesion

cell adhesion mediated by integrin

cell-cell adhesion

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

integrin-mediated signaling pathway

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

cellular developmental process [inference]

cell differentiation [inference]

ectodermal cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

cell junction disassembly [inference]

synapse pruning [inference]

complement-mediated synapse pruning

cell junction organization [inference]

synapse organization [inference]

synapse pruning [inference]

complement-mediated synapse pruning

cell junction disassembly [inference]

synapse pruning [inference]

complement-mediated synapse pruning

membrane organization [inference]

membrane invagination [inference]

plasma membrane invagination [inference]

phagocytosis, engulfment

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

pattern specification process [inference]

regionalization [inference]

vertebrate eye-specific patterning

amyloid-beta clearance

developmental process [inference]

anatomical structure development [inference]

forebrain development

cellular developmental process [inference]

cell differentiation [inference]

ectodermal cell differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

response to Gram-positive bacterium

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

response to ischemia

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to mechanical stimulus

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

response to Gram-positive bacterium

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

response to Gram-positive bacterium

defense response to other organism [inference]

innate immune response

response to abiotic stimulus [inference]

response to mechanical stimulus

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to lipid [inference]

response to estradiol

response to ether [inference]

response to curcumin

response to ketone [inference]

response to curcumin

response to oxygen-containing compound [inference]

response to estradiol

response to ether [inference]

response to curcumin

response to ketone [inference]

response to curcumin

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of myeloid leukocyte mediated immunity [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of myeloid leukocyte mediated immunity [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of leukocyte mediated immunity [inference]

regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

regulation of microglial cell mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of myeloid leukocyte mediated immunity [inference]

regulation of myeloid leukocyte mediated immunity [inference]

positive regulation of myeloid leukocyte mediated immunity [inference]

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

regulation of microglial cell mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amine metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of reactive oxygen species metabolic process [inference]

regulation of superoxide metabolic process [inference]

regulation of superoxide anion generation [inference]

positive regulation of superoxide anion generation

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of nitrogen compound metabolic process [inference]

regulation of amine metabolic process [inference]

negative regulation of amine metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amine metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of primary metabolic process [inference]

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of protein localization to membrane [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of myeloid leukocyte mediated immunity [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amine metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

integrin-mediated signaling pathway

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of reactive oxygen species metabolic process [inference]

regulation of superoxide metabolic process [inference]

regulation of superoxide anion generation [inference]

positive regulation of superoxide anion generation

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of cell killing [inference]

regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

regulation of microglial cell mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of protein localization to membrane [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of isomerase activity [inference]

positive regulation of prostaglandin-E synthase activity

regulation of catalytic activity [inference]

regulation of isomerase activity [inference]

positive regulation of isomerase activity [inference]

positive regulation of prostaglandin-E synthase activity

regulation of prostaglandin-E synthase activity [inference]

positive regulation of prostaglandin-E synthase activity

positive regulation of catalytic activity [inference]

positive regulation of isomerase activity [inference]

positive regulation of prostaglandin-E synthase activity

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GO Term	Evidence Code	PMID
specific granule membrane	TAS
plasma membrane	IDA TAS	28807980
extracellular space	IDA	25645918
integrin alphaM-beta2 complex	IPI ISS	18083624
integrin complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphaM-beta2 complex

protein complex involved in cell adhesion [inference]

integrin complex

integrin alphaM-beta2 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphaM-beta2 complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

bounding membrane of organelle [inference]

secretory granule membrane [inference]

plasma membrane region [inference]

plasma membrane raft

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

side of membrane [inference]

external side of plasma membrane

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GO Term	Evidence Code	PMID
integrin binding	IBA NAS	20199584
amyloid-beta binding	IC
metal ion binding	IEA
protein binding	IPI	12208882 15004192 15194813 16246332 21193407 28939773 32296183 38730209
heat shock protein binding	IPI	12496435

GO Hierarchy

molecular function

binding [inference]

protein binding

opsonin binding [inference]

complement component C3b binding

complement binding [inference]

complement component C3b binding

signaling receptor binding [inference]

integrin binding

heat shock protein binding

cell adhesion molecule binding [inference]

integrin binding

amide binding [inference]

peptide binding [inference]

amyloid-beta binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

cargo receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

integrin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
cell adhesion mediated by integrin
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 7** entries
InterPro
FG-GAP repeat
Integrin alpha beta-propellor
Integrin alpha chain
Integrin alpha, N-terminal
Integrin alpha, first immunoglubulin-like domain
Integrin alpha, second immunoglobulin-like domain
Integrin domain superfamily

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050852	limb ischemia	Alliance of Genome Resources
DOID:0060224	atrial fibrillation	Alliance of Genome Resources
DOID:0060903	thrombosis	Alliance of Genome Resources
DOID:0080162	lupus nephritis	Alliance of Genome Resources
DOID:10591	pre-eclampsia	Alliance of Genome Resources
DOID:1168	familial hyperlipidemia	Alliance of Genome Resources
DOID:11713	diabetic angiopathy	Alliance of Genome Resources
DOID:1227	neutropenia	Alliance of Genome Resources
DOID:13042	persistent fetal circulation syndrome	Alliance of Genome Resources
DOID:13241	Behcet's disease	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	16409		MGI:96607	MOUSE53739
Rattus norvegicus	25021		RGD:2926	RATNO17090
Bos taurus	407124			BOVIN20653
Ovis aries	443217			SHEEP12464
Pan troglodytes	454069	9598_0:00432c		PANTR12231
Canis lupus familiaris	489928			CANLF16358
Danio rerio	563715		ZFIN:ZDB-GENE-110510-4
Macaca mulatta	714832			MACMU27314
Monodelphis domestica	100016833			MONDO29597
Equus caballus	100064803			HORSE07045

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements