GlyCosmos Portal

Submissions

integrin subunit alpha M

Summary

Gene Symbol

ITGAM

Organism

Homo sapiens (human)

External Links

NCBI Gene

3684

PubChem

3684

Alliance of Genome Resources

HGNC:6149

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Cell adhesion
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Innate immunity
Integrin
Magnesium
Metal-binding
Receptor
Reference proteome
Repeat
Signal
Systemic lupus erythematosus
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P11215	CD11 antigen-like family member B CR-3 alpha chain Cell surface glycoprotein MAC-1 subunit alpha Leukocyte adhesion receptor MO1 Neutrophil adherence receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
cell-matrix adhesion	IBA IDA	18083624
cell-cell adhesion	IBA
amyloid-beta clearance	ISS
microglial cell activation	ISS
positive regulation of protein targeting to membrane	ISS

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response [inference]

innate immune response

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

cell adhesion

cell-substrate adhesion [inference]

cell-matrix adhesion

cell adhesion mediated by integrin

cell-cell adhesion

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

integrin-mediated signaling pathway

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

cellular developmental process [inference]

cell differentiation [inference]

ectodermal cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

cell junction disassembly [inference]

synapse pruning [inference]

complement-mediated synapse pruning

cell junction organization [inference]

synapse organization [inference]

synapse pruning [inference]

complement-mediated synapse pruning

cell junction disassembly [inference]

synapse pruning [inference]

complement-mediated synapse pruning

membrane organization [inference]

membrane invagination [inference]

plasma membrane invagination [inference]

phagocytosis, engulfment

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

pattern specification process [inference]

regionalization [inference]

vertebrate eye-specific patterning

amyloid-beta clearance

developmental process [inference]

anatomical structure development [inference]

forebrain development

cellular developmental process [inference]

cell differentiation [inference]

ectodermal cell differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

response to Gram-positive bacterium

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

response to ischemia

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to mechanical stimulus

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

response to Gram-positive bacterium

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

response to Gram-positive bacterium

defense response to other organism [inference]

innate immune response

response to abiotic stimulus [inference]

response to mechanical stimulus

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to lipid [inference]

response to estradiol

response to ether [inference]

response to curcumin

response to ketone [inference]

response to curcumin

response to oxygen-containing compound [inference]

response to estradiol

response to ether [inference]

response to curcumin

response to ketone [inference]

response to curcumin

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of myeloid leukocyte mediated immunity [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of myeloid leukocyte mediated immunity [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of leukocyte mediated immunity [inference]

regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

regulation of microglial cell mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of myeloid leukocyte mediated immunity [inference]

regulation of myeloid leukocyte mediated immunity [inference]

positive regulation of myeloid leukocyte mediated immunity [inference]

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

regulation of microglial cell mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amine metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of reactive oxygen species metabolic process [inference]

regulation of superoxide metabolic process [inference]

regulation of superoxide anion generation [inference]

positive regulation of superoxide anion generation

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of nitrogen compound metabolic process [inference]

regulation of amine metabolic process [inference]

negative regulation of amine metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amine metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of primary metabolic process [inference]

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of protein localization to membrane [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of myeloid leukocyte mediated immunity [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

positive regulation of metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amine metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

positive regulation of neutrophil degranulation

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

complement receptor mediated signaling pathway

integrin-mediated signaling pathway

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of catecholamine metabolic process [inference]

regulation of dopamine metabolic process [inference]

negative regulation of dopamine metabolic process

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of reactive oxygen species metabolic process [inference]

regulation of superoxide metabolic process [inference]

regulation of superoxide anion generation [inference]

positive regulation of superoxide anion generation

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

regulation of cell killing [inference]

regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

regulation of microglial cell mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of reactive oxygen species metabolic process [inference]

positive regulation of superoxide anion generation

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of microglial cell mediated cytotoxicity

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of catecholamine metabolic process [inference]

negative regulation of dopamine metabolic process

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein targeting [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of protein localization to membrane [inference]

regulation of protein targeting to membrane [inference]

positive regulation of protein targeting to membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein targeting to membrane

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of regulated secretory pathway [inference]

regulation of leukocyte degranulation [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of neutrophil degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

positive regulation of secretion by cell [inference]

positive regulation of exocytosis [inference]

positive regulation of regulated secretory pathway [inference]

positive regulation of leukocyte degranulation [inference]

positive regulation of neutrophil degranulation

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of isomerase activity [inference]

positive regulation of prostaglandin-E synthase activity

regulation of catalytic activity [inference]

regulation of isomerase activity [inference]

positive regulation of isomerase activity [inference]

positive regulation of prostaglandin-E synthase activity

regulation of prostaglandin-E synthase activity [inference]

positive regulation of prostaglandin-E synthase activity

positive regulation of catalytic activity [inference]

positive regulation of isomerase activity [inference]

positive regulation of prostaglandin-E synthase activity

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GO Term	Evidence Code	PMID
external side of plasma membrane	IBA NAS	20199584
plasma membrane raft	IDA	21193407
plasma membrane	IDA TAS	28807980
tertiary granule membrane	TAS
integrin alphaM-beta2 complex	IPI ISS	18083624

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphaM-beta2 complex

protein complex involved in cell adhesion [inference]

integrin complex

integrin alphaM-beta2 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alphaM-beta2 complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

bounding membrane of organelle [inference]

secretory granule membrane [inference]

plasma membrane region [inference]

plasma membrane raft

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

side of membrane [inference]

external side of plasma membrane

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GO Term	Evidence Code	PMID
protein binding	IPI	12208882 15004192 15194813 16246332 21193407 28939773 32296183 38730209
integrin binding	IBA NAS	20199584
complement component C3b binding	ISS
heat shock protein binding	IPI	12496435
metal ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

opsonin binding [inference]

complement component C3b binding

complement binding [inference]

complement component C3b binding

signaling receptor binding [inference]

integrin binding

heat shock protein binding

cell adhesion molecule binding [inference]

integrin binding

amide binding [inference]

peptide binding [inference]

amyloid-beta binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

cargo receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

integrin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
cell adhesion mediated by integrin
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 7** entries
InterPro
FG-GAP repeat
Integrin alpha beta-propellor
Integrin alpha chain
Integrin alpha, N-terminal
Integrin alpha, first immunoglubulin-like domain
Integrin alpha, second immunoglobulin-like domain
Integrin domain superfamily

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050852	limb ischemia	Alliance of Genome Resources
DOID:0060224	atrial fibrillation	Alliance of Genome Resources
DOID:0060903	thrombosis	Alliance of Genome Resources
DOID:0080162	lupus nephritis	Alliance of Genome Resources
DOID:10591	pre-eclampsia	Alliance of Genome Resources
DOID:1168	familial hyperlipidemia	Alliance of Genome Resources
DOID:11713	diabetic angiopathy	Alliance of Genome Resources
DOID:1227	neutropenia	Alliance of Genome Resources
DOID:13042	persistent fetal circulation syndrome	Alliance of Genome Resources
DOID:13241	Behcet's disease	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	16409		MGI:96607	MOUSE53739
Rattus norvegicus	25021		RGD:2926	RATNO17090
Bos taurus	407124			BOVIN20653
Ovis aries	443217			SHEEP12464
Pan troglodytes	454069	9598_0:00432c		PANTR12231
Canis lupus familiaris	489928			CANLF16358
Danio rerio	563715		ZFIN:ZDB-GENE-110510-4
Macaca mulatta	714832			MACMU27314
Monodelphis domestica	100016833			MONDO29597
Equus caballus	100064803			HORSE07045

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements