lysyl-tRNA synthetase 1

Summary
Gene Symbol
  • KARS1
Organism
Homo sapiens (human)
NCBI Gene
3735
PubChem
3735
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Alternative splicing
  • Aminoacyl-tRNA synthetase
  • Cell membrane
  • Charcot-Marie-Tooth disease
  • Cytoplasm
  • Direct protein sequencing
  • Disease variant
  • Host-virus interaction
  • Intellectual disability
  • Mitochondrion
  • Neurodegeneration
  • Non-syndromic deafness
  • Nucleus
  • Phosphoprotein
  • Protein biosynthesis
  • Reference proteome
  • Secreted
  • Transferase
Proteins
Displaying 1 entry
UniProt Protein Name
Q15046
  • Lysyl-tRNA synthetase
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0110204 Charcot-Marie-Tooth disease recessive intermediate B
DOID:0110534 autosomal recessive nonsyndromic deafness 89

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025