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galectin 3

Summary

Gene Symbol

LGALS3

Organism

Gallus gallus (chicken)

External Links

NCBI Gene: 373917
KEGG Gene ID: gga:373917
PubChem: 373917

Annotation

Keyword

Acetylation
Disulfide bond
IgE-binding protein
Lectin
Secreted
Spliceosome

Proteins

Displaying 1 entry
UniProt	Protein Name
A4GTP0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
monocyte chemotaxis	IEA	30032202
neutrophil chemotaxis	IEA	30032202
eosinophil chemotaxis	IEA	30032202
positive regulation of calcium ion import	IEA	30032202
negative regulation of extrinsic apoptotic signaling pathway	IEA	30032202

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

mononuclear cell migration [inference]

monocyte chemotaxis

myeloid leukocyte migration [inference]

monocyte chemotaxis

granulocyte migration [inference]

granulocyte chemotaxis [inference]

eosinophil migration [inference]

eosinophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

macrophage migration [inference]

macrophage chemotaxis

cellular process [inference]

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

mononuclear cell migration [inference]

monocyte chemotaxis

myeloid leukocyte migration [inference]

monocyte chemotaxis

granulocyte migration [inference]

granulocyte chemotaxis [inference]

eosinophil migration [inference]

eosinophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

macrophage migration [inference]

macrophage chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

locomotion [inference]

taxis [inference]

chemotaxis [inference]

positive chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

regulation of calcium ion import [inference]

positive regulation of calcium ion import

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

Displaying **all 4** entries
GO Term	Evidence Code	PMID
collagen-containing extracellular matrix	IEA	30032202
immunological synapse	IEA	30032202
extracellular space	IEA	30032202
nucleus	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
IgE binding	IEA	30032202
laminin binding	IEA	30032202
carbohydrate binding	IEA	22301074

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

laminin binding

carbohydrate binding

protein-containing complex binding [inference]

immunoglobulin binding [inference]

IgE binding

extracellular matrix binding [inference]

laminin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

galectin

Functional Category

K: Transcription
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
IgE binding
eosinophil chemotaxis
macrophage chemotaxis
monocyte chemotaxis
negative regulation of endocytosis
negative regulation of extrinsic apoptotic signaling pathway
neutrophil chemotaxis
positive chemotaxis
positive regulation of calcium ion import

Displaying **all 3** entries
InterPro
Concanavalin A-like lectin/glucanase domain superfamily
Galectin, carbohydrate recognition domain
Galectin-like

KEGG BRITE Database

Orthology

K06831

Name

galectin-3

References

2261464

Ortholog

Displaying entries **1 - 10** of 14 in total

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Species	Gene ID	OrthoDB
Meleagris gallopavo	100548598	9103_1:00185f
Anas platyrhynchos	101805160	8839_0:0017bb
Anser cygnoides	106044050	8845_0:001316
Coturnix japonica	107315455	93934_0:001850
Numida meleagris	110401138	8996_0:001aeb
Phasianus colchicus	116236653	9054_0:0028a3
Aythya fuligula	116489914	219594_0:00170c
Oxyura jamaicensis	118168574	8884_0:001801
Cygnus atratus	118250304	8868_0:0016fc
Cygnus olor	121070876	8869_0:001953