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mannose binding lectin 2

Summary

Gene Symbol

MBL2

Organism

Gallus gallus (chicken)

External Links

NCBI Gene: 374267
KEGG Gene ID: gga:374267
PubChem: 374267

Annotation

Keyword

Calcium
Collagen
Complement activation lectin pathway
Complement pathway
Disulfide bond
Glycoprotein
Hydroxylation
Mannose-binding
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q98TA4	Mannan-binding protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
positive regulation of phagocytosis	IEA	30032202
complement activation, lectin pathway
surfactant homeostasis	IEA	30032202
complement activation, classical pathway

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

complement activation [inference]

activation of immune response [inference]

complement activation [inference]

immune response [inference]

humoral immune response [inference]

complement activation [inference]

innate immune response [inference]

complement activation, lectin pathway

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, lectin pathway

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, lectin pathway

immune response [inference]

humoral immune response [inference]

complement activation [inference]

innate immune response [inference]

complement activation, lectin pathway

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, lectin pathway

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

complement activation, lectin pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

Displaying **all 5** entries
GO Term	Evidence Code	PMID
multivesicular body	IEA	30032202
extracellular region
collagen trimer
extracellular space	IEA	30032202
rough endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

collagen trimer

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

rough endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum [inference]

rough endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

Displaying 1 entry
GO Term	Evidence Code	PMID
mannose binding

GO Hierarchy

molecular function

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

mannose binding

small molecule binding [inference]

monosaccharide binding [inference]

mannose binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Lectin

Functional Category

O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
C-type lectin fold
C-type lectin-like/link domain superfamily
C-type lectin-like

Ortholog

Displaying entries **1 - 10** of 14 in total

1

2

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Species	Gene ID	OrthoDB
Meleagris gallopavo	100549167	9103_1:001e63
Anas platyrhynchos	101797467	8839_0:001c47
Anser cygnoides	106032387	8845_0:002009
Coturnix japonica	107315596	93934_0:001c19
Numida meleagris	110400309	8996_0:001809
Phasianus colchicus	116234730	9054_0:002319
Aythya fuligula	116491281	219594_0:001abc
Oxyura jamaicensis	118169107	8884_0:001af7
Cygnus atratus	118246060	8868_0:001b78
Cygnus olor	121072846	8869_0:001cf0