GlyCosmos Portal

Submissions

alpha-L-fucosidase

Summary

Gene Symbol

Fuca

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

3772574

PubChem

3772574

Alliance of Genome Resources

FB:FBgn0285958

Annotation

Keyword

Glycoprotein
Glycosidase
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VTJ4	Alpha-L-fucoside fucohydrolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
glycosaminoglycan catabolic process	NAS	11698403
glycoside catabolic process	IBA
carbohydrate metabolic process	IEA
defense response to bacterium	IMP	18245331
fucose metabolic process	IBA IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

glycosyl compound metabolic process [inference]

glycoside metabolic process [inference]

glycoside catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process

cellular process [inference]

cell recognition [inference]

cell-cell recognition [inference]

sperm-egg recognition [inference]

binding of sperm to zona pellucida

reproductive process [inference]

sperm-egg recognition [inference]

binding of sperm to zona pellucida

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

Displaying **all 3** entries
GO Term	Evidence Code	PMID
outer acrosomal membrane	IDA	26101846
sperm plasma membrane	IDA	26101846
lysosome	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane [inference]

sperm plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

outer acrosomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
alpha-L-fucosidase activity	IDA IEA TAS	11698403 16736526
fucose binding	IDA	21708168

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

fucosidase activity [inference]

alpha-L-fucosidase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

fucose binding

small molecule binding [inference]

monosaccharide binding [inference]

fucose binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
sperm plasma membrane	PMID:26101846
membrane	FB:FBrf0231198
outer acrosomal membrane	PMID:26101846

Rhea

RHEA:12288

H₂O + an α-L-fucoside

L-fucose + an alcohol

Enzyme

3.2.1.51

PMID

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:14500	fucosidosis	Alliance of Genome Resources
DOID:8947	diabetic retinopathy	Alliance of Genome Resources
DOID:9351	diabetes mellitus	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources
DOID:9744	type 1 diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 11 in total

1

2

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	189173	WB:WBGene00012225
Danio rerio	335494	ZFIN:ZDB-GENE-030131-7434
Danio rerio	445165	ZFIN:ZDB-GENE-040801-78
Danio rerio	445487	ZFIN:ZDB-GENE-040822-39
Xenopus tropicalis	496744	Xenbase:XB-GENE-945131
Homo sapiens	2517	HGNC:4006
Homo sapiens	2519	HGNC:4008
Mus musculus	66848	MGI:1914098
Mus musculus	71665	MGI:95593
Rattus norvegicus	24375	RGD:2636