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Peroxidasin

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

38326

PubChem

38326

Alliance of Genome Resources

FB:FBgn0011828

Annotation

Keyword

Alternative splicing
Calcium
Coiled coil
Disulfide bond
Glycoprotein
Heme
Hydrogen peroxide
Immunoglobulin domain
Leucine-rich repeat
Peroxidase
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
D2NUH5
Q9VZZ4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
phagocytosis	IMP	8062820
response to oxidative stress	IEA
extracellular matrix organization	IMP	8062820
collagen fibril organization	IMP	22842973
hydrogen peroxide catabolic process

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

hydrogen peroxide catabolic process

organic substance catabolic process [inference]

hydrogen peroxide catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

hydrogen peroxide catabolic process

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

organic substance metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

organic substance catabolic process [inference]

hydrogen peroxide catabolic process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

cellular metabolic process [inference]

cellular catabolic process [inference]

hydrogen peroxide catabolic process

reactive oxygen species metabolic process [inference]

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

extracellular matrix assembly [inference]

basement membrane assembly

extracellular structure organization [inference]

extracellular matrix organization

collagen fibril organization

basement membrane organization [inference]

basement membrane assembly

extracellular matrix assembly [inference]

basement membrane assembly

external encapsulating structure organization [inference]

extracellular matrix organization

collagen fibril organization

basement membrane organization [inference]

basement membrane assembly

extracellular matrix assembly [inference]

basement membrane assembly

supramolecular fiber organization [inference]

collagen fibril organization

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

import into cell [inference]

endocytosis [inference]

phagocytosis

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IBA
collagen-containing extracellular matrix	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

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GO Term	Evidence Code	PMID
peroxidase activity	IBA
peroxidase activity	IEA
oxidoreductase activity, acting on peroxide as acceptor	ISS	22842973
heme binding	IEA
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on peroxide as acceptor

peroxidase activity

lactoperoxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

antioxidant activity [inference]

peroxidase activity

lactoperoxidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

peroxidase

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cellular oxidant detoxification
heme binding
metal ion binding
response to oxidative stress

Displaying **all 3** entries
InterPro
Haem peroxidase domain superfamily, animal type
Haem peroxidase superfamily
Haem peroxidase, animal-type

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
membrane	FB:FBrf0231198
basement membrane	PMID:8062820

Ortholog

Displaying entries **1 - 10** of 12 in total

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Species	Gene ID	Alliance of Genome Resources
Danio rerio	4025	ZFIN:ZDB-GENE-030131-9460
Danio rerio	4353	ZFIN:ZDB-GENE-030131-9460
Xenopus tropicalis	7837	Xenbase:XB-GENE-923300
Danio rerio	8288	ZFIN:ZDB-GENE-030131-9460
Danio rerio	13861	ZFIN:ZDB-GENE-030131-9460
Danio rerio	17523	ZFIN:ZDB-GENE-030131-9460
Xenopus tropicalis	38326	Xenbase:XB-GENE-923300
Xenopus tropicalis	69675	Xenbase:XB-GENE-923300
Homo sapiens	137902	HGNC:26359
Xenopus tropicalis	181288	Xenbase:XB-GENE-923300

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Annotation

OrthoDB (Group)

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Acknowledgements