GlyCosmos Portal

Submissions

colonial temperature sensitive-5

Summary

Gene Symbol

cot-5

Organism

Neurospora crassa OR74A

External Links

NCBI Gene: 3871987
KEGG Gene ID: ncr:NCU03503
PubChem: 3871987

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8X0H8	Asparagine-linked glycosylation protein 2 GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oligosaccharide-lipid intermediate biosynthetic process
protein glycosylation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
alpha-1,3-mannosyltransferase activity	IEA	30032202
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity	IEA	30032202
GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

mannosyltransferase activity [inference]

alpha-1,3-mannosyltransferase activity

glycolipid mannosyltransferase activity [inference]

GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity

GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha-

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
GDP-Man
GDP-Man
alpha-1,3-mannosyltransferase activity
oligosaccharide-lipid intermediate biosynthetic process
transferase activity

Displaying **all 3** entries
InterPro
Glycosyl transferase, family 1
Glycosyltransferase subfamily 4-like, N-terminal domain
Mannosyltransferase ALG2

KEGG BRITE Database

Orthology

K03843

Name

alpha-1,3/alpha-1,6-mannosyltransferase [EC:2.4.1.132 2.4.1.257]

References

12684507

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05973	2.4.1.132	G65996GC	G53394BX
R06238	2.4.1.257	G53394BX	G43547MI

Rhea

RHEA:29519

GDP-α-D-mannose

H⁺ + GDP

Enzyme

2.4.1.257

PMID

RHEA:29515

GDP-α-D-mannose

H⁺ + GDP

Enzyme

2.4.1.132

PMID

Ortholog

Displaying **all 8** entries
Species	Gene ID	OrthoDB
Chaetomium globosum CBS 148.51	4393526	306901_0:000d53
Podospora anserina S mat+	6194741	515849_0:0021bf
Sordaria macrospora k-hell	10801970	771870_0:001f97
Thermothelomyces thermophilus ATCC 42464	11506671	573729_0:002324
Thermothielavioides terrestris NRRL 8126	11522058	578455_0:002434
Thermochaetoides thermophila DSM 1495	18254749	759272_0:00027b
Neurospora tetrasperma FGSC 2508	20829171	510951_0:001248
Lasiosphaeria miniovina	85323757	1954250_0:0030ea

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements