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MIRAGE
hypocretin (orexin) receptor 2
Summary
- Gene Symbol
-
- Hcrtr2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P58308 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor signaling pathway | ||
| phospholipase C-activating G protein-coupled receptor signaling pathway | ||
| neuropeptide signaling pathway | ||
| neuropeptide signaling pathway | ||
| neuropeptide signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleoplasm | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor activity | ||
| protein binding | ||
| orexin receptor activity | ||
| orexin receptor activity | ||
| orexin receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Orexin receptor 2
- Functional Category
-
- C: Energy production and conversion
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| circadian sleep/wake cycle process |
| orexin receptor activity |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
| Orexin receptor 2 |
| Orexin receptor family |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:8986 | narcolepsy |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3061 | WB:WBGene00012275 | ||
| 3062 | Xenbase:XB-GENE-952341 | HUMAN85259 | |
| 25593 | WB:WBGene00012275 | ||
| 25605 | Xenbase:XB-GENE-952341 | RATNO41214 | |
| 230777 | WB:WBGene00012275 | ||
| 387285 | Xenbase:XB-GENE-952341 | ||
| 397428 | PIGXX31315 | ||
| 399545 | CANLF02870 | ||
| 462786 | PANTR38432 | ||
| 529603 | BOVIN18219 |
