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MIRAGE
ras homolog family member A
Summary
- Gene Symbol
-
- RHOA
- Aliases
-
- RHOH12
- Rho12
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ADP-ribosylation
- Cell division
- Cell membrane
- Cell projection
- Cytoskeleton
- Direct protein sequencing
- Disease variant
- Ectodermal dysplasia
- GTP-binding
- Glycoprotein
- Host-virus interaction
- Hydrolase
- Isopeptide bond
- Lipoprotein
- Magnesium
- Membrane
- Methylation
- Nucleus
- Phosphoprotein
- Prenylation
- Proteomics identification
- Proto-oncogene
- Reference proteome
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P61586 |
|
| B4DKN9 |
|
| A0A024R324 |
|
| C9JX21 |
|
| C9JRM1 |
|
| A0A7I2YQV1 |
|
| Q9BVT0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| motor neuron apoptotic process | ||
| endothelial tube lumen extension | ||
| regulation of modification of postsynaptic structure | ||
| regulation of modification of postsynaptic structure | ||
| positive regulation of non-canonical NF-kappaB signal transduction |
GO Hierarchy
biological process
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of epithelial cell migration [inference]
regulation of system process [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| GTPase activity | ||
| GTPase activity | ||
| GTPase activity | ||
| GTPase activity | ||
| G protein activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- cell division control protein 42
- Functional Category
-
- T: Signal transduction mechanisms
- U: Intracellular trafficking, secretion, and vesicular transport
| Gene Ontology |
|---|
| GTP binding |
| nucleotide binding |
| protein kinase binding |
| small GTPase-mediated signal transduction |
| InterPro |
|---|
| P-loop containing nucleoside triphosphate hydrolase |
| Small GTP-binding protein domain |
| Small GTPase Rho |
| Small GTPase |
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3459 | breast carcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000648 | Optic atrophy |
| HP:0000677 | Oligodontia |
| HP:0000689 | Dental malocclusion |
| HP:0000691 | Microdontia |
| HP:0000698 | Conical tooth |
| HP:0001156 | Brachydactyly |
| HP:0001249 | Intellectual disability |
| HP:0001263 | Global developmental delay |
| HP:0001442 | Typified by somatic mosaicism |
| HP:0001852 | Sandal gap |
| Disease ID | Disease Name |
|---|---|
| OMIM:618727 |
|
PubChem Disease
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100393236 | CALJA11691 | ||
| 100607291 | NOMLE28615 | ||
| 100894614 | CALJA11691 | ||
| 101052068 | SAIBB27176 | ||
| 103250976 | CARSF30948 | ||
| 104667372 | RHIRO13997 | ||
| 105819379 | PROCO00264 | ||
| 105874961 | MICMU02313 | ||
| 105878757 | MICMU02313 |
