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UDP glucuronosyltransferase 1 family, polypeptide A7C

Summary

Gene Symbol

Ugt1a7c

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

394432

KEGG Gene ID

mmu:394432

PubChem

394432

Alliance of Genome Resources

MGI:3032636

Annotation

Keyword

Alternative splicing
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Lipid metabolism
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6ZQM8	UDP-glucuronosyltransferase 1-7C UDP-glucuronosyltransferase 1A7C

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
catabolic process	ISO
coumarin catabolic process	ISO
aromatic compound catabolic process
cellular glucuronidation	IBA
liver development	IBA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process

hormone catabolic process [inference]

estrogen catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

secondary metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

hormone metabolic process [inference]

estrogen metabolic process

estrogen catabolic process

hormone catabolic process [inference]

estrogen catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

heterocycle metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

estrogen metabolic process

estrogen catabolic process

lipid catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

estrogen metabolic process

estrogen catabolic process

lipid catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

estrogen metabolic process

estrogen catabolic process

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

heterocycle metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

gland development [inference]

liver development

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

estrogen metabolic process

estrogen catabolic process

hormone catabolic process [inference]

estrogen catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IBA ISO
endoplasmic reticulum membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
steroid binding	ISO
enzyme binding	IBA ISO
protein homodimerization activity	ISO
protein kinase C binding	ISO
fatty acid binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

protein binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase C binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding

organic cyclic compound binding [inference]

steroid binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00699

Name

glucuronosyltransferase [EC:2.4.1.17]

References

Rhea

glucuronate acceptor + UDP-α-D-glucuronate

acceptor β-D-glucuronoside + H⁺ + UDP

Enzyme

2.4.1.17

PMID

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:4947	cholangiocarcinoma	Alliance of Genome Resources
DOID:4988	alcoholic pancreatitis	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	175591	WB:WBGene00010904
Caenorhabditis elegans	178330	WB:WBGene00007455
Drosophila melanogaster	35137	FB:FBgn0027074
Drosophila melanogaster	35138	FB:FBgn0032713
Drosophila melanogaster	35139	FB:FBgn0027070
Drosophila melanogaster	37420	FB:FBgn0027073
Drosophila melanogaster	40079	FB:FBgn0036842
Drosophila melanogaster	41333	FB:FBgn0026314
Drosophila melanogaster	41334	FB:FBgn0026315
Drosophila melanogaster	41574	FB:FBgn0038083

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024