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UDP glucuronosyltransferase 1 family, polypeptide A7C

Summary

Gene Symbol

Ugt1a7c

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

394432

KEGG Gene ID

mmu:394432

PubChem

394432

Alliance of Genome Resources

MGI:3032636

Annotation

Keyword

Alternative splicing
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Lipid metabolism
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6ZQM8	UDP-glucuronosyltransferase 1-7C UDP-glucuronosyltransferase 1A7C

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
estrogen catabolic process	ISO
estrogen metabolic process

GO Hierarchy

biological process

metabolic process [inference]

catabolic process

hormone catabolic process [inference]

estrogen catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

secondary metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

hormone metabolic process [inference]

estrogen metabolic process

estrogen catabolic process

hormone catabolic process [inference]

estrogen catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

heterocycle metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

estrogen metabolic process

estrogen catabolic process

lipid catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

estrogen metabolic process

estrogen catabolic process

lipid catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

estrogen metabolic process

estrogen catabolic process

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process [inference]

estrogen catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

heterocycle metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

gland development [inference]

liver development

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

estrogen metabolic process

estrogen catabolic process

hormone catabolic process [inference]

estrogen catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IBA ISO
endoplasmic reticulum membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
steroid binding	ISO
enzyme binding	IBA ISO
protein homodimerization activity	ISO
protein kinase C binding	ISO
fatty acid binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

protein binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase C binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

fatty acid binding

organic cyclic compound binding [inference]

steroid binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00699

Name

glucuronosyltransferase [EC:2.4.1.17]

References

Rhea

glucuronate acceptor + UDP-α-D-glucuronate

acceptor β-D-glucuronoside + H⁺ + UDP

Enzyme

2.4.1.17

PMID

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:4947	cholangiocarcinoma	Alliance of Genome Resources
DOID:4988	alcoholic pancreatitis	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **51 - 60** of 68 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mandrillus leucophaeus	105539813		MANLE03253
Gorilla gorilla gorilla	101146584		GORGO26611
Pan paniscus	100975751		PANPA26933
Pan troglodytes	107973969		PANTR30077
Pongo abelii	100172533		PONAB24971
Pongo abelii	100172560		PONAB24971
Pongo abelii	100173720		PONAB24971
Homo sapiens	54575	HGNC:12531	HUMAN67632
Homo sapiens	54576	HGNC:12540	HUMAN67631
Homo sapiens	54577	HGNC:12539	HUMAN67635

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024