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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
leptin
Summary
- Gene Symbol
-
- LEP
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of T cell proliferation | ||
| regulation of insulin secretion | ||
| positive regulation of MAPK cascade | ||
| negative regulation of lipid storage | ||
| negative regulation of appetite by leptin-mediated signaling pathway |
GO Hierarchy
- positive regulation of cold-induced thermogenesis
- positive regulation of cold-induced thermogenesis
- regulation of cell cycle
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of system process [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding | ||
| hormone activity | ||
| peptide hormone receptor binding | ||
| protein binding | ||
| leptin receptor binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1612 | breast cancer | |
| DOID:1924 | hypogonadism | |
| DOID:2018 | hyperinsulinism | |
| DOID:2841 | asthma | |
| DOID:2913 | acute pancreatitis | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3146 | lipid metabolism disorder | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:4450 | renal cell carcinoma | |
| DOID:4483 | rhinitis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102366460 | LATCH05119 | ||
| 564348 | ZFIN:ZDB-GENE-041210-183 | ||
| 100150233 | ZFIN:ZDB-GENE-081001-1 | ||
| 734226 | Xenbase:XB-GENE-980662 | ||
| 108711253 | Xenbase:XB-GENE-17342421 | ||
| 113450645 | PSETE24636 | ||
| 100078019 | ORNAN00888 | ||
| 100930199 | SARHA04155 | ||
| 103116410 | ERIEU08504 | ||
| 100407456 | CALJA42753 |
