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galectin 4

Summary

Gene Symbol

LGALS4

Aliases

GAL4

Organism

Homo sapiens (human)

External Links

NCBI Gene

3960

HGNC

6565

KEGG Gene ID

hsa:3960

PubChem

3960

Alliance of Genome Resources

HGNC:6565

Annotation

Keyword

3D-structure
Lectin
Phosphoprotein
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P56470	Antigen NY-CO-27 L-36 lactose-binding protein Lactose-binding lectin 4
Q6FHZ4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
antibacterial peptide biosynthetic process	IEA
cell adhesion		9162064

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

organic substance metabolic process [inference]

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

cellular process [inference]

cell adhesion

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

antimicrobial peptide biosynthetic process [inference]

antibacterial peptide biosynthetic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytosol		9162064
plasma membrane		9162064
collagen-containing extracellular matrix	HDA	25037231
extracellular space	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

Displaying **all 3** entries
GO Term	Evidence Code	PMID
galactoside binding	IEA
carbohydrate binding	IBA
protein binding	IPI	26481311 32296183

GO Hierarchy

molecular function

binding [inference]

carbohydrate derivative binding [inference]

galactoside binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000171747

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K10091

Name

galectin-4

References

9310382

Disease

Disease Ontology

Displaying entries **1 - 10** of **100** in total

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DO ID	Disease Name	Source
DOID:0050424	familial adenomatous polyposis	DisGeNET
DOID:0050463	campomelic dysplasia	DisGeNET
DOID:0050589	inflammatory bowel disease	DisGeNET DisGeNET
DOID:0050819	obsolete Matthew-Wood syndrome	DisGeNET
DOID:0060192	Crohn's colitis	DisGeNET
DOID:0060891	Parkinson's disease 19A	DisGeNET
DOID:0060895	Parkinson's disease 4	DisGeNET
DOID:0060896	Parkinson's disease 23	DisGeNET
DOID:0080033	craniometaphyseal dysplasia	DisGeNET
DOID:0080199	colorectal carcinoma	DisGeNET

Ortholog

Displaying entries **1 - 10** of 50 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	174557	WB:WBGene00002266
Caenorhabditis elegans	174964	WB:WBGene00002264
Caenorhabditis elegans	178548	WB:WBGene00017080
Drosophila melanogaster	33162	FB:FBgn0031213
Drosophila melanogaster	33163	FB:FBgn0031214
Danio rerio	567193	ZFIN:ZDB-GENE-141222-13
Ictalurus punctatus	124627891		ICTPU27838
Electrophorus electricus	113576599		ELEEL19052
Salmo trutta	115206694		SALTR110305
Salmo trutta	115206695		SALTR110305

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024