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methylsterol monooxygenase 1

Summary

Gene Symbol

MSMO1

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 396590
KEGG Gene ID: ssc:396590
PubChem: 396590

Annotation

Keyword

Cholesterol biosynthesis
Endoplasmic reticulum
Iron
Monooxygenase
NAD
Oxidoreductase
Reference proteome
Sterol biosynthesis
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
D0G7F0
Q6UGB2	C-4 methylsterol oxidase Sterol-C4-methyl oxidase
A0A8D0VTM9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
sterol biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

sterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

sterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

sterol metabolic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound metabolic process [inference]

sterol metabolic process [inference]

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
C-4 methylsterol oxidase activity	IEA	30032202
iron ion binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen [inference]

C-4 methylsterol oxidase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen [inference]

C-4 methylsterol oxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K07750

Name

methylsterol monooxygenase [EC:1.14.18.9]

References

Rhea

H⁺ + O₂ + 4,4-dimethyl-5α-cholest-7-en-3β-ol

H₂O + 4α-carboxy-4β-methyl-5α-cholest-7-ene-3β-ol

Enzyme

1.14.18.9

PMID

Ortholog

Displaying entries **41 - 50** of 93 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Bos taurus	504481		BOVIN09015
Capra hircus	102180413		CAPHI08140
Ovis aries	101121628		SHEEP07097
Oryctolagus cuniculus	100343167		RABIT14111
Oryctolagus cuniculus	127489716		RABIT14111
Dipodomys ordii	105991105		DIPOR00929
Cricetulus griseus	100754784		CRIGR06663
Mus musculus	66234		MOUSE58689
Rattus norvegicus	140910		RATNO11178
Cavia porcellus	100721665		CAVPO00713

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024