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Guidelines

MIRAGE

LIF interleukin 6 family cytokine

Summary

Gene Symbol

LIF

Organism

Homo sapiens (human)

External Links

NCBI Gene

3976

PubChem

3976

Alliance of Genome Resources

HGNC:6596

Annotation

Keyword

3D-structure
Alternative splicing
Cytokine
Direct protein sequencing
Disulfide bond
Glycoprotein
Growth factor
Pharmaceutical
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P15018	Differentiation-stimulating factor Melanoma-derived LPL inhibitor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 42 in total

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GO Term	Evidence Code	PMID
cell morphogenesis	IEA
response to hypoxia	IEA
blood vessel remodeling	IEA
immune response	IEA
embryo implantation	IEA

GO Hierarchy

biological process

immune system process [inference]

immune response

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

leukemia inhibitory factor signaling pathway

receptor signaling pathway via STAT

cell population proliferation [inference]

fibroblast proliferation

cell cycle process [inference]

meiotic cell cycle process [inference]

meiotic nuclear division

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation

stem cell differentiation

cell differentiation involved in embryonic placenta development [inference]

cell development [inference]

neuron development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle fission [inference]

nuclear division [inference]

meiotic nuclear division

reproductive process [inference]

developmental process involved in reproduction [inference]

decidualization

cell differentiation involved in embryonic placenta development [inference]

embryo implantation

meiotic cell cycle process [inference]

meiotic nuclear division

multicellular organismal process [inference]

stem cell population maintenance [inference]

somatic stem cell population maintenance

tissue remodeling [inference]

blood vessel remodeling

developmental process [inference]

developmental process involved in reproduction [inference]

decidualization

cell differentiation involved in embryonic placenta development [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

animal organ morphogenesis [inference]

muscle organ morphogenesis

lung lobe morphogenesis

anatomical structure development [inference]

tissue development [inference]

decidualization

lung alveolus development

cell development [inference]

neuron development

system development [inference]

vasculature development [inference]

lung vasculature development

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

macrophage differentiation

stem cell differentiation

cell differentiation involved in embryonic placenta development [inference]

cell development [inference]

neuron development

maintenance of cell number [inference]

stem cell population maintenance [inference]

somatic stem cell population maintenance

response to stimulus [inference]

response to stress [inference]

response to hypoxia

immune response

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of hormone secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of fibroblast proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of cell adhesion [inference]

positive regulation of cell adhesion mediated by integrin

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of hormone secretion

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of hormone secretion

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of morphogenesis of an epithelium [inference]

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of cell differentiation

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of epithelial cell differentiation involved in kidney development [inference]

regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of nephron tubule epithelial cell differentiation [inference]

regulation of metanephric nephron tubule epithelial cell differentiation

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of glial cell differentiation [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

regulation of astrocyte differentiation [inference]

positive regulation of astrocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of epithelial cell differentiation involved in kidney development [inference]

regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of nephron tubule epithelial cell differentiation [inference]

regulation of metanephric nephron tubule epithelial cell differentiation

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

leukemia inhibitory factor signaling pathway

receptor signaling pathway via STAT

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of MAPK cascade

regulation of ERK1 and ERK2 cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of hormone secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion

regulation of cell adhesion [inference]

regulation of cell adhesion mediated by integrin [inference]

positive regulation of cell adhesion mediated by integrin

positive regulation of cell adhesion [inference]

positive regulation of cell adhesion mediated by integrin

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of fibroblast proliferation

negative regulation of cell population proliferation

regulation of fibroblast proliferation [inference]

positive regulation of fibroblast proliferation

regulation of cell differentiation

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of epithelial cell differentiation involved in kidney development [inference]

regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of nephron tubule epithelial cell differentiation [inference]

regulation of metanephric nephron tubule epithelial cell differentiation

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of glial cell differentiation [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

regulation of astrocyte differentiation [inference]

positive regulation of astrocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of fibroblast proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of cell adhesion [inference]

positive regulation of cell adhesion mediated by integrin

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of MAPK cascade [inference]

negative regulation of ERK1 and ERK2 cascade

negative regulation of hormone secretion

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

regulation of nuclear division [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of multicellular organismal development [inference]

regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation [inference]

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of epithelial cell differentiation involved in kidney development [inference]

regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of nephron tubule epithelial cell differentiation [inference]

regulation of metanephric nephron tubule epithelial cell differentiation

positive regulation of epithelial cell differentiation involved in kidney development [inference]

positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell differentiation [inference]

positive regulation of astrocyte differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of macrophage differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of macrophage differentiation

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular space	IC	12643274
extracellular space	IBA
cytosol	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	IPI	8999038
cytokine activity	IDA	20624457 22783022 7957045
cytokine activity	IBA
leukemia inhibitory factor receptor binding	IDA	7957045
leukemia inhibitory factor receptor binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

cytokine receptor binding [inference]

leukemia inhibitory factor receptor binding

receptor ligand activity [inference]

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Leukemia inhibitory factor

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 8** entries
Gene Ontology
cytokine activity
growth factor activity
immune response
leukemia inhibitory factor receptor binding
leukemia inhibitory factor signaling pathway
positive regulation of cell population proliferation
regulation of cell differentiation
signaling receptor binding

Displaying **all 3** entries
InterPro
Four-helical cytokine-like, core
Leukemia inhibitory factor /oncostatin
Leukemia inhibitory factor

Ortholog

Displaying entries **1 - 10** of 57 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	3976	Xenbase:XB-GENE-984971
Mus musculus	16878	Xenbase:XB-GENE-984971	MOUSE06347
Rattus norvegicus	60584		RATNO08010
Bos taurus	280840		BOVIN09819
Sus scrofa	399503		PIGXX07157
Canis lupus familiaris	403449		CANLF10470
Macaca mulatta	715456		MACMU00903
Pan troglodytes	736309		PANTR26310
Monodelphis domestica	100018708		MONDO19961
Oryctolagus cuniculus	100358914		RABIT14780

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Last updated: April 7, 2025