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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
LIF interleukin 6 family cytokine
Summary
- Gene Symbol
-
- LIF
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Growth factor
- Pharmaceutical
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P15018 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of fibroblast proliferation | ||
| positive regulation of cell population proliferation | ||
| cell morphogenesis | ||
| embryo implantation | ||
| regulation of metanephric nephron tubule epithelial cell differentiation |
GO Hierarchy
biological process
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell differentiation
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| cytosol |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| leukemia inhibitory factor receptor binding | ||
| signaling receptor binding | ||
| cytokine activity | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- leukemia inhibitory factor
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
| InterPro |
|---|
| Four-helical cytokine-like, core |
| Leukemia inhibitory factor /oncostatin |
| Leukemia inhibitory factor |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 16878 | MGI:96787 | MOUSE06347 | ||
| 60584 | RGD:620865 | RATNO08010 | ||
| 280840 | BOVIN09819 | |||
| 399503 | PIGXX07157 | |||
| 403449 | CANLF10470 | |||
| 715456 | MACMU00903 | |||
| 736309 | 9598_0:00549a | PANTR26310 | ||
| 100018708 | MONDO19961 | |||
| 100358914 | RABIT14780 | |||
| 100381055 | Xenbase:XB-GENE-984972 |
