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fibroblast growth factor receptor 1 S homeolog

Summary

Gene Symbol

fgfr1.S

Organism

Xenopus laevis (African clawed frog)

External Links

NCBI Gene

397782

PubChem

397782

Alliance of Genome Resources

Xenbase:XB-GENE-6254218

Annotation

Keyword

ATP-binding
Alternative splicing
Cell membrane
Cytoplasm
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Immunoglobulin domain
Nucleus
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Proteins

Displaying **all 4** entries
UniProt	Protein Name
P22182
A0A974D967
B7ZRE2
A0A1L8GRK9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
positive regulation of cell population proliferation
animal organ development
positive regulation of cell differentiation
regulation of macromolecule metabolic process
cell differentiation

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation

developmental process [inference]

anatomical structure development [inference]

animal organ development

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of macromolecule metabolic process

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of developmental process [inference]

positive regulation of cell differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation

positive regulation of cellular process [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasmic vesicle
receptor complex
plasma membrane
nucleus
cytosol

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying **all 3** entries
GO Term	Evidence Code	PMID
fibroblast growth factor binding
ATP binding
fibroblast growth factor receptor activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

binding [inference]

protein binding [inference]

growth factor binding [inference]

fibroblast growth factor binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity [inference]

fibroblast growth factor receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Fibroblast growth factor receptor

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ATP binding
fibroblast growth factor receptor activity
nucleotide binding
transmembrane receptor protein tyrosine kinase activity

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InterPro
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain

Disease

Disease Ontology

Displaying entries **1 - 10** of 22 in total

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DO ID	Disease Name	Source
DOID:0060597	atypical chronic myeloid leukemia, BCR-ABL1 negative	Alliance of Genome Resources
DOID:0070004	myeloid neoplasm	Alliance of Genome Resources
DOID:0081312	T-cell non-Hodgkin lymphoma	Alliance of Genome Resources
DOID:0090078	hypogonadotropic hypogonadism 7 with or without anosmia	Alliance of Genome Resources
DOID:0090083	hypogonadotropic hypogonadism 2 with or without anosmia	Alliance of Genome Resources
DOID:0111337	Jackson-Weiss syndrome	Alliance of Genome Resources
DOID:0111532	osteoglophonic dysplasia	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:12689	acoustic neuroma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **251** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	2260		HGNC:3688
Homo sapiens	2263	9606_0:004666
Gallus gallus	396259	9031_0:001e9f
Gallus gallus	396515	9031_0:00175f
Gallus gallus	396516	9031_0:003622
Sus scrofa	396762	9823_0:003e49
Bos taurus	404193	9913_0:0048ba
Canis lupus familiaris	415125	9615_0:0044bf
Xenopus tropicalis	548648	8364_0:00178b	Xenbase:XB-GENE-1018554
Macaca mulatta	715949	9544_0:0026ad

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements