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phospholipase A2 group XV

Summary

Gene Symbol

PLA2G15

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 403403
KEGG Gene ID: cfa:403403
PubChem: 403403

Annotation

Keyword

Acyltransferase
Disulfide bond
Fatty acid metabolism
Glycoprotein
Hydrolase
Lysosome
Membrane
Metal-binding
Reference proteome
Secreted
Signal
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6XPZ3	1-O-acylceramide synthase LCAT-like lysophospholipase Lysophospholipase 3 Lysosomal phospholipase A2 Phospholipase A2 group XV

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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2

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GO Term	Evidence Code	PMID
fatty acid metabolic process
glycerophospholipid metabolic process
diacylglycerol biosynthetic process
phosphatidylserine metabolic process
ceramide metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

sphingolipid metabolic process [inference]

ceramide metabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

glycerophospholipid metabolic process

phosphatidylserine metabolic process

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process

glycerophospholipid catabolic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

diacylglycerol biosynthetic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular space	IEA	30032202
nucleoplasm
lysosome	IEA	30032202
membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
lysophospholipase activity
zinc ion binding
O-acyltransferase activity	IEA	22301074 30032202
phospholipase A1 activity
acylglycerol O-acyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity

acylglycerol O-acyltransferase activity

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

lysophospholipase activity

phospholipase A2 activity [inference]

calcium-independent phospholipase A2 activity

carboxylic ester hydrolase activity [inference]

lysophospholipase activity

phospholipase A2 activity [inference]

calcium-independent phospholipase A2 activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

group XV phospholipase a2

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 2** entries
Gene Ontology
O-acyltransferase activity
lipid metabolic process

Displaying **all 2** entries
InterPro
Alpha/Beta hydrolase fold
Lecithin

KEGG BRITE Database

Orthology

K06129

Name

lysophospholipase III [EC:3.1.1.5]

References

10092508

Rhea

RHEA:15801

H₂O + a 1,2-diacyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + a 1-acyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

RHEA:15177

H₂O + a 1-acyl-sn-glycero-3-phosphocholine

H⁺ + sn-glycerol 3-phosphocholine + a fatty acid

Enzyme

3.1.1.5

PMID

RHEA:18689

H₂O + a 1,2-diacyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + a 2-acyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.32

PMID

RHEA:36231

H₂O + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + 1-O-alkyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

9442064

Ortholog

Displaying entries **11 - 20** of 76 in total

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Species	Gene ID	Orthologous MAtrix
Oryctolagus cuniculus	100355284	RABIT11004
Callithrix jacchus	100393262	CALJA21553
Ailuropoda melanoleuca	100477335	AILME08742
Nomascus leucogenys	100593427	NOMLE26072
Loxodonta africana	100658599	LOXAF07400
Oreochromis niloticus	100695535	ORENI69884
Cavia porcellus	100727869	CAVPO10853
Cricetulus griseus	100760699	CRIGR12566
Otolemur garnettii	100966301	OTOGA03875
Pan paniscus	100986534	PANPA15491

GlyTouCan

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UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements