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MIRAGE
lymphotoxin alpha
Summary
- Gene Symbol
-
- LTA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytokine
- Direct protein sequencing
- Glycoprotein
- Membrane
- Proteomics identification
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P01374 |
|
| Q5STV3 |
|
| Q6FG55 |
|
| Q5ST95 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia | ||
| positive regulation of chronic inflammatory response to antigenic stimulus | ||
| positive regulation of humoral immune response mediated by circulating immunoglobulin | ||
| apoptotic process | ||
| immune response |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| cytokine activity | ||
| tumor necrosis factor receptor binding | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- lymphotoxin alpha
- Functional Category
-
- K: Transcription
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| humoral immune response |
| immune response |
| tumor necrosis factor receptor binding |
| InterPro |
|---|
| Lymphotoxin-alpha |
| Tumour necrosis factor domain |
| Tumour necrosis factor, conserved site |
| Tumour necrosis factor-like domain superfamily |
| Tumour necrosis factor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050127 | sinusitis | |
| DOID:0050697 | chorioamnionitis | |
| DOID:0080750 | erythema nodosum | |
| DOID:1024 | leprosy | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:1205 | allergic disease | |
| DOID:12361 | Graves' disease | |
| DOID:12894 | Sjogren's syndrome | |
| DOID:13258 | typhoid fever | |
| DOID:13406 | pulmonary sarcoidosis |
