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leukotriene C4 synthase
Summary
- Gene Symbol
-
- LTC4S
- Aliases
-
- MGC33147
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Endoplasmic reticulum
- Leukotriene biosynthesis
- Lipid biosynthesis
- Lyase
- Nucleus
- Phosphoprotein
- Reference proteome
- Transferase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q16873 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| leukotriene metabolic process | ||
| leukotriene biosynthetic process | ||
| long-chain fatty acid biosynthetic process | ||
| cellular oxidant detoxification |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear envelope | ||
| nuclear envelope | ||
| nuclear envelope | ||
| nuclear outer membrane | ||
| endoplasmic reticulum |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| glutathione transferase activity | ||
| leukotriene-C4 synthase activity | ||
| leukotriene-C4 synthase activity | ||
| glutathione peroxidase activity | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- microsomal glutathione
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| glutathione transferase activity |
Rhea
Disease
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000252 | Microcephaly |
| HP:0001252 | Hypotonia |
| HP:0001263 | Global developmental delay |
| HP:0001522 | Death in infancy |
| HP:0001531 | Failure to thrive in infancy |
| Disease ID | Disease Name |
|---|---|
| OMIM:614037 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002479
- Gene Name
- leukotriene C4 synthase
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 4056 | Xenbase:XB-GENE-981579 | ||
| 17001 | MOUSE04754 | ||
| 511749 | BOVIN32046 | ||
| 607316 | CANLF01974 | ||
| 705233 | MACMU39557 | ||
| 100032154 | MONDO05921 | ||
| 100520063 | PIGXX19090 | ||
| 100535432 | DANRE07600 | ||
| 100675058 | LOXAF20381 | ||
| 100701372 | ORENI46127 |
