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Standards Ontologies Notations
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2

Summary
Gene Symbol
  • st6gal2
Organism
Xenopus tropicalis (tropical clawed frog)
NCBI Gene
407846
KEGG Gene ID
xtr:407846
PubChem
407846
Alliance of Genome Resources
Annotation
Keyword
  • Glycoprotein
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Transferase
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
A8KBE9
  • CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2
  • ST6Gal II
  • Sialyltransferase 2
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
KEGG BRITE Database
Orthology
K00779
Name
beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.3.1]
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R06188
Rhea

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP
Enzyme
PMID

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP
Enzyme
PMID

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0070129 autosomal recessive cutis laxa type IID
DOID:0112275 developmental and epileptic encephalopathy 93
Ortholog
Displaying entries 1 - 10 of 216 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
523 HGNC:851
11964 MGI:1201780
34695 FB:FBgn0032464
37950 FB:FBgn0035050
45012 FB:FBgn0263598
45668 FB:FBgn0265262
84620 9606_0:003cdf HGNC:10861
240119 MGI:2445190
301155 RGD:1559663
337583 ZFIN:ZDB-GENE-030131-9529
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024