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Guidelines

MIRAGE

protein phosphatase 1, catalytic subunit, gamma isozyme

Summary

Gene Symbol

ppp1cc

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

NCBI Gene

407879

PubChem

407879

Alliance of Genome Resources

Xenbase:XB-GENE-967934

Annotation

Keyword

Centromere
Chromosome
Cytoskeleton
Glycogen metabolism
Kinetochore
Manganese
Metal-binding
Mitochondrion
Mitosis
Nucleus
Protein phosphatase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6NVU2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cell division	IEA
protein dephosphorylation	ISS
mitotic nuclear membrane reassembly	ISS
glycogen metabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

cell cycle process [inference]

mitotic cell cycle process [inference]

mitotic nuclear membrane organization [inference]

mitotic nuclear membrane reassembly

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

membrane assembly [inference]

nuclear membrane reassembly [inference]

mitotic nuclear membrane reassembly

membrane organization [inference]

membrane assembly [inference]

nuclear membrane reassembly [inference]

mitotic nuclear membrane reassembly

nuclear membrane organization [inference]

nuclear membrane reassembly [inference]

mitotic nuclear membrane reassembly

mitotic nuclear membrane organization [inference]

mitotic nuclear membrane reassembly

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
nucleus	IBA IEA
nuclear speck	IEA
chromosome	IEA
cytoplasm	IBA IEA
kinetochore	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

cleavage furrow

nuclear body [inference]

nuclear speck

midbody

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosomal region [inference]

chromosome, centromeric region

supramolecular complex [inference]

kinetochore

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein serine/threonine phosphatase activity	IBA IEA ISS
metal ion binding	IEA
myosin phosphatase activity	IEA
phosphoprotein phosphatase activity	IEA
hydrolase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity

protein serine/threonine phosphatase activity

myosin phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity

protein serine/threonine phosphatase activity

myosin phosphatase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Phosphatase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
hydrolase activity
phosphoprotein phosphatase activity

Displaying **all 4** entries
InterPro
Calcineurin-like phosphoesterase domain, ApaH type
Metallo-dependent phosphatase-like
Serine/Threonine protein phosphatase PP2A-like
Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:162	cancer	Alliance of Genome Resources
DOID:6000	congestive heart failure	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **588** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5499	9606_0:0029be
Homo sapiens	5500	9606_0:00262d
Homo sapiens	5501	9606_0:002577	HGNC:9283
Mus musculus	19047		MGI:104872
Rattus norvegicus	24669		RGD:3377
Drosophila melanogaster	42922		FB:FBgn0003134
Drosophila melanogaster	48531		FB:FBgn0003132
Drosophila melanogaster	49260		FB:FBgn0004103
Bos taurus	282318	9913_0:003343
Xenopus laevis	379914	8355_0:007db9

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.1

Last updated: February 17, 2025