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ATPase H+ transporting accessory protein 2

Summary

Gene Symbol

ATP6AP2

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

41104

KEGG Gene ID

dme:Dmel_CG8444

PubChem

41104

Alliance of Genome Resources

FB:FBgn0037671

Annotation

Keyword

Cell membrane
Cleavage on pair of basic residues
Endoplasmic reticulum
Golgi apparatus
Receptor
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VHG4	Renin homolog receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
vacuolar proton-transporting V-type ATPase complex assembly	IGI	29995586
establishment of imaginal disc-derived wing hair orientation	IMP	23292348
synapse organization	IMP	26376863
axonal transport	IMP	26376863
establishment of body hair or bristle planar orientation	IMP	23292348

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport

vesicle-mediated transport [inference]

endosomal transport

cellular localization [inference]

intracellular transport [inference]

endosomal transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization involved in establishment of planar polarity

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

proton-transporting two-sector ATPase complex assembly [inference]

proton-transporting V-type ATPase complex assembly [inference]

vacuolar proton-transporting V-type ATPase complex assembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

non-sensory hair organization [inference]

imaginal disc-derived wing hair organization

cell junction organization [inference]

synapse organization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

proton-transporting two-sector ATPase complex assembly [inference]

proton-transporting V-type ATPase complex assembly [inference]

vacuolar proton-transporting V-type ATPase complex assembly

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory [inference]

behavior [inference]

learning or memory [inference]

memory [inference]

developmental process [inference]

anatomical structure morphogenesis [inference]

establishment of tissue polarity [inference]

establishment of planar polarity

post-embryonic animal morphogenesis [inference]

establishment of imaginal disc-derived wing hair orientation

anatomical structure development [inference]

animal organ development [inference]

sensory organ development [inference]

eye development [inference]

compound eye development

locomotion [inference]

taxis [inference]

energy taxis [inference]

phototaxis

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

phototaxis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization involved in establishment of planar polarity

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

vesicle-mediated transport [inference]

endosomal transport

intracellular transport [inference]

endosomal transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport

cellular localization [inference]

intracellular transport [inference]

endosomal transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization involved in establishment of planar polarity

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
external side of plasma membrane	IBA
endoplasmic reticulum membrane	IDA	29995586
apical part of cell	IDA	23292348
cell surface	IDA	23292348
plasma membrane	IDA	20579883

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex [inference]

vacuolar proton-transporting V-type ATPase complex

catalytic complex [inference]

ATPase complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex [inference]

vacuolar proton-transporting V-type ATPase complex

cellular anatomical entity [inference]

cell surface

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

apical part of cell

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
signaling receptor activity	IEA
frizzled binding	IDA	20579883

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

frizzled binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K19514

Name

renin receptor

References

25374826

Alliance of Genome Resources

Expression

Displaying **all 6** entries
Location	References
plasma membrane	PMID:20579883
Golgi membrane	PMID:29995586
apical part of cell	PMID:23292348
cell surface	PMID:23292348
membrane	FB:FBrf0231198
endoplasmic reticulum membrane	PMID:29995586

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0050571	congenital disorder of glycosylation type II	Alliance of Genome Resources
DOID:0060309	syndromic X-linked intellectual disability	Alliance of Genome Resources
DOID:0060806	syndromic X-linked intellectual disability Hedera type	Alliance of Genome Resources
DOID:0112105	X-linked parkinsonism-spasticity syndrome	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:5212	congenital disorder of glycosylation	Alliance of Genome Resources

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	174109	WB:WBGene00020500
Caenorhabditis elegans	181526	WB:WBGene00010993
Danio rerio	406296	ZFIN:ZDB-GENE-040426-1960
Xenopus tropicalis	496778	Xenbase:XB-GENE-964301
Homo sapiens	10159	HGNC:18305
Mus musculus	70495	MGI:1917745
Rattus norvegicus	302526	RGD:1561269