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steroid sulfatase
Summary
- Gene Symbol
-
- STS
- Aliases
-
- ARSC
- arylsulfatase C
- steryl-sulfatase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cytoplasmic vesicle
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Hydrolase
- Ichthyosis
- Metal-binding
- Pregnancy
- Proteomics identification
- Reference proteome
- Signal
- Steroid metabolism
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A6PYA4 |
|
| P08842 |
|
| A0A590UJL0 |
|
| Q0W975 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| steroid catabolic process | ||
| female pregnancy | ||
| epidermis development |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum | ||
| plasma membrane | ||
| endosome | ||
| Golgi apparatus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| steryl-sulfatase activity | ||
| metal ion binding | ||
| sulfuric ester hydrolase activity | ||
| arylsulfatase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- arylsulfatase
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| sulfuric ester hydrolase activity |
| InterPro |
|---|
| Alkaline-phosphatase-like, core domain superfamily |
| Sulfatase, N-terminal |
| Sulfatase, conserved site |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10763 | hypertension | |
| DOID:11383 | cryptorchidism | |
| DOID:1700 | X-linked ichthyosis |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000028 | Cryptorchidism |
| HP:0000083 | Renal insufficiency |
| HP:0000122 | Unilateral renal agenesis |
| HP:0000135 | Hypogonadism |
| HP:0000717 | Autism |
| HP:0000958 | Dry skin |
| HP:0000962 | Hyperkeratosis |
| HP:0000966 | Hypohidrosis |
| HP:0000982 | Palmoplantar keratoderma |
| HP:0001249 | Intellectual disability |
| Disease ID | Disease Name |
|---|---|
| OMIM:308100 |
|
| ORPHA:281090 |
|
| ORPHA:461 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP006680
- Gene Name
- steroid sulfatase (microsomal), isozyme S
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 20905 | MGI:98438 | |||
| 24800 | RGD:3783 | RATNO44293 | ||
| 179194 | WB:WBGene00006309 | |||
| 402795 | ZFIN:ZDB-GENE-030717-5 | DANRE16756 | ||
| 448816 | PIGXX36886 | |||
| 465478 | 9598_0:00555f | PANTR45445 | ||
| 491727 | CANLF19542 | |||
| 509206 | BOVIN37501 | |||
| 707799 | MACMU47270 | |||
| 100034102 | HORSE43795 |
