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methionyl-tRNA synthetase 1

Summary

Gene Symbol

MARS1

Organism

Homo sapiens (human)

External Links

NCBI Gene

4141

PubChem

4141

Alliance of Genome Resources

HGNC:6898

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Aminoacyl-tRNA synthetase
Charcot-Marie-Tooth disease
Cytoplasm
Disease variant
Hereditary spastic paraplegia
Nucleus
Phosphoprotein
Protein biosynthesis
Reference proteome
tRNA-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
P56192	Methionyl-tRNA synthetase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
tRNA aminoacylation for protein translation	TAS
rRNA transcription	IMP	10791971
cellular response to platelet-derived growth factor stimulus	IDA	10791971
positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	IMP	10791971
cellular response to epidermal growth factor stimulus	IDA	10791971

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid activation [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA aminoacylation [inference]

tRNA aminoacylation for protein translation

methionyl-tRNA aminoacylation

rRNA metabolic process [inference]

rRNA transcription

ncRNA transcription [inference]

rRNA transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

ncRNA transcription [inference]

rRNA transcription

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

response to platelet-derived growth factor [inference]

cellular response to platelet-derived growth factor stimulus

response to epidermal growth factor [inference]

cellular response to epidermal growth factor stimulus

cellular response to growth factor stimulus [inference]

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

regulation of ncRNA transcription [inference]

regulation of transcription of nucleolar large rRNA by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
membrane	HDA	19946888
aminoacyl-tRNA synthetase multienzyme complex	IBA IDA	10791971 19131329
cytosol	IBA IDA TAS	19289464
cytoplasm	IDA	10791971 22424946
extracellular exosome	HDA	20458337

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

aminoacyl-tRNA synthetase multienzyme complex

catalytic complex [inference]

aminoacyl-tRNA synthetase multienzyme complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
methionine-tRNA ligase activity	IBA IDA TAS	11714285
tRNA binding	IEA
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-oxygen bonds [inference]

aminoacyl-tRNA ligase activity [inference]

methionine-tRNA ligase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

aminoacyl-tRNA ligase activity [inference]

methionine-tRNA ligase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

tRNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

methionine--trna ligase

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
V: Defense mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
ligase activity
methionine-tRNA ligase activity
methionyl-tRNA aminoacylation
nucleotide binding
tRNA aminoacylation for protein translation

Displaying **all 9** entries
InterPro
Aminoacyl-tRNA synthetase, class I, conserved site
Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
Methionine-tRNA ligase, type 1
Methioninyl-tRNA synthetase core domain
Methionyl-tRNA synthetase, Zn-domain
Methionyl-tRNA synthetase, anticodon-binding domain
Methionyl-tRNA synthetase
Methionyl/Leucyl tRNA synthetase
Rossmann-like alpha/beta/alpha sandwich fold

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0070454	hereditary spastic paraplegia 70	Alliance of Genome Resources
DOID:0110173	Charcot-Marie-Tooth disease axonal type 2U	Alliance of Genome Resources
DOID:0111866	trichothiodystrophy	Alliance of Genome Resources
DOID:12120	pulmonary alveolar proteinosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 79 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	37177		FB:FBgn0034401
Caenorhabditis elegans	178089		WB:WBGene00003415
Mus musculus	216443		MGI:1345633	MOUSE00860
Rattus norvegicus	299851		RGD:1305321	RATNO39080
Danio rerio	338183		ZFIN:ZDB-GENE-030219-83	DANRE38639
Xenopus laevis	379675		Xenbase:XB-GENE-17340220
Xenopus laevis	446558		Xenbase:XB-GENE-5952584
Pan troglodytes	452016	9598_0:003453		PANTR05485
Canis lupus familiaris	474414			CANLF01346
Bos taurus	512531			BOVIN29567

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements