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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Acetylcholine esterase
Summary
- Gene Symbol
-
- Ace
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Neurotransmitter degradation
- Proteomics identification
- Reference proteome
- Serine esterase
- Signal
- Synapse
- Proteins
| UniProt | Protein Name |
|---|---|
| E1JIJ8 |
|
| A0A0B4KGI5 |
|
| P07140 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine catabolic process in synaptic cleft | ||
| acetylcholine catabolic process | ||
| choline metabolic process | ||
| choline catabolic process | ||
| chemical synaptic transmission |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| side of membrane |
|
|
| synaptic cleft |
|
|
| extracellular space | ||
| synapse |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| cholinesterase activity | ||
| sulfate binding | ||
| serine hydrolase activity | ||
| peptidase activity | ||
| acetylcholinesterase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- acetylcholinesterase
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| acetylcholine catabolic process |
| acetylcholinesterase activity |
| choline metabolic process |
| cholinesterase activity |
| hydrolase activity |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase type B, active site |
| Carboxylesterase type B, conserved site |
| Carboxylesterase, type B |
| Cholinesterase |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050784 | primary progressive multiple sclerosis | |
| DOID:10113 | trypanosomiasis | |
| DOID:10487 | Hirschsprung's disease | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:10914 | amnestic disorder | |
| DOID:1168 | familial hyperlipidemia | |
| DOID:12858 | Huntington's disease | |
| DOID:1307 | dementia | |
| DOID:14330 | Parkinson's disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 43 | HGNC:108 | |||
| 590 | HGNC:983 | |||
| 11423 | MGI:87876 | |||
| 12038 | MGI:894278 | |||
| 65036 | RGD:619996 | |||
| 83817 | RGD:69313 | |||
| 114549 | ZFIN:ZDB-GENE-010906-1 | |||
| 171905 | WB:WBGene00000036 | |||
| 181706 | WB:WBGene00000035 | |||
| 4801388 | 7237_1:0007c2 |
