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sulfide-dependent adenosine diphosphate thiazole synthase

Summary

Gene Symbol

PFDSM3638_RS07735

Organism

Pyrococcus furiosus DSM 3638

External Links

NCBI Gene: 41713349
PubChem: 41713349

Annotation

Keyword

Iron
Isomerase
Metal-binding
NAD
Reference proteome
Thiamine biosynthesis
Transferase

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A5C0XTG6
I6U8B7
Q8U0Q5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
thiamine biosynthetic process
thiamine diphosphate biosynthetic process
thiazole biosynthetic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organonitrogen compound metabolic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

oxazole or thiazole metabolic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound metabolic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organic cyclic compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organonitrogen compound metabolic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

primary alcohol biosynthetic process [inference]

thiamine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiazole metabolic process [inference]

thiazole biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiazole biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

oxazole or thiazole metabolic process [inference]

oxazole or thiazole biosynthetic process [inference]

thiazole biosynthetic process

thiazole metabolic process [inference]

thiazole biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process [inference]

thiamine biosynthetic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
iron ion binding
pentosyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

pentosyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:55704

hydrogen sulfide + glycine + NAD⁺

ADP-5-ethyl-4-methylthiazole-2-carboxylate + H₂O + H⁺ + nicotinamide

Enzyme

2.4.2.59

PMID

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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External Links

Annotation

International Collaboration

Acknowledgements