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Dopamine 1-like receptor 1

Summary

Gene Symbol

Dop1R1

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

41726

PubChem

41726

Alliance of Genome Resources

FB:FBgn0011582

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A0A0B4KHI2
A0A126GUU2
A0A0B4K6H0
P41596	Dopamine 1-like receptor 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 20 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IBA
dopamine receptor signaling pathway	ISS	10908591
response to odorant	IMP	26687359
cellular response to sucrose stimulus	IDA	22304923
regulation of presynaptic cytosolic calcium ion concentration	IMP	26687359

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

dopamine receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning

associative learning

memory

behavior [inference]

learning or memory [inference]

learning

associative learning

memory

visual behavior [inference]

visual learning

chemosensory behavior [inference]

olfactory behavior

olfactory learning

thermosensory behavior

locomotion [inference]

taxis [inference]

thermotaxis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

neuron cellular homeostasis [inference]

regulation of presynaptic cytosolic calcium ion concentration

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of presynaptic cytosolic calcium ion concentration

response to stimulus [inference]

response to stress [inference]

response to starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to starvation

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

response to chemical [inference]

response to organic substance [inference]

response to carbohydrate [inference]

response to disaccharide [inference]

response to sucrose

cellular response to sucrose stimulus

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to disaccharide [inference]

response to sucrose

cellular response to sucrose stimulus

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

response to odorant

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to disaccharide stimulus [inference]

cellular response to sucrose stimulus

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of response to stimulus [inference]

regulation of olfactory learning

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating dopamine receptor signaling pathway

dopamine receptor signaling pathway

adenylate cyclase-activating dopamine receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

regulation of olfactory learning

regulation of behavior [inference]

regulation of olfactory learning

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IEA ISS	10908591
presynapse
plasma membrane	IBA ISM	7953290
dendrite	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

presynapse

Displaying **all 5** entries
GO Term	Evidence Code	PMID
dopamine neurotransmitter receptor activity	ISS	10908591
neurotransmitter receptor activity	IBA
G protein-coupled serotonin receptor activity	IBA
G protein-coupled receptor activity	IEA ISS	12163486
dopamine neurotransmitter receptor activity, coupled via Gs	IDA IMP	7720859 7953290

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled amine receptor activity [inference]

G protein-coupled serotonin receptor activity

neurotransmitter receptor activity

postsynaptic neurotransmitter receptor activity [inference]

dopamine neurotransmitter receptor activity

dopamine neurotransmitter receptor activity, coupled via Gs

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
membrane	FB:FBrf0231198

Disease

Disease Ontology

Displaying entries **1 - 10** of 19 in total

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DO ID	Disease Name	Source
DOID:0050741	alcohol dependence	Alliance of Genome Resources
DOID:0060001	withdrawal disorder	Alliance of Genome Resources
DOID:0060040	pervasive developmental disorder	Alliance of Genome Resources
DOID:0081292	traumatic brain injury	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:1074	kidney failure	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:1094	attention deficit hyperactivity disorder	Alliance of Genome Resources
DOID:12858	Huntington's disease	Alliance of Genome Resources
DOID:14330	Parkinson's disease	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 50 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Danio rerio	100001636		ZFIN:ZDB-GENE-121214-145
Danio rerio	100002285		ZFIN:ZDB-GENE-060526-372
Xenopus tropicalis	100124855		Xenbase:XB-GENE-5919679
Xenopus tropicalis	100485463		Xenbase:XB-GENE-6035431
Drosophila suzukii	108016407	28584_1:002a79
Drosophila biarmipes	108032143	125945_1:00299c
Drosophila rhopaloa	108049318	1041015_1:001789
Drosophila takahashii	108060158	29030_0:00151e
Drosophila kikkawai	108075708	30033_1:000c80
Drosophila ficusphila	108091870	30025_0:00007c