MDM2 proto-oncogene

Summary
Gene Symbol
  • MDM2
Organism
Homo sapiens (human)
NCBI Gene
4193
PubChem
4193
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Apoptosis
  • Cytoplasm
  • Host-virus interaction
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Proto-oncogene
  • Reference proteome
  • Transferase
  • Ubl conjugation
  • Ubl conjugation pathway
  • Zinc-finger
Proteins
Displaying all 7 entries
UniProt Protein Name
A7UKX8
G3XA89
  • Double minute 2 protein
  • RING-type E3 ubiquitin transferase Mdm2
  • p53-binding protein Mdm2
A0A0A8KB75
  • Double minute 2 protein
  • RING-type E3 ubiquitin transferase Mdm2
  • p53-binding protein Mdm2
A7UKX9
Q96DS0
Q00987
  • Double minute 2 protein
  • Oncoprotein Mdm2
  • RING-type E3 ubiquitin transferase Mdm2
  • p53-binding protein Mdm2
A7UKX7
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
E3 ubiquitin-protein ligase Mdm2
Functional Category
  • E: Amino acid transport and metabolism
  • L: Replication, recombination and repair
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:1115 sarcoma
DOID:3068 glioblastoma
DOID:3587 pancreatic ductal carcinoma
DOID:684 hepatocellular carcinoma
DOID:8552 chronic myeloid leukemia

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025