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delta

Summary

Gene Symbol

Delta

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

42313

PubChem

42313

Alliance of Genome Resources

FB:FBgn0000463

Annotation

Keyword

3D-structure
Developmental protein
Differentiation
Disulfide bond
EGF-like domain
Glycoprotein
Neurogenesis
Notch signaling pathway
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P10041
A4V346

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 41 in total

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GO Term	Evidence Code	PMID
cell fate specification	TAS	11735386
actin filament organization	IMP	16049109
cell communication	IEA
Notch signaling pathway	IDA	10935637 15611340
Notch signaling pathway	IMP	16093323 1657403 17157832 17287246 20203305 23970418 28960177 8600026 8756291 9202123 9310337 9553038 9872749

GO Hierarchy

biological process

cellular process [inference]

cell cycle [inference]

mitotic cell cycle [inference]

second mitotic wave involved in compound eye morphogenesis

cell communication

cell-cell signaling [inference]

cell-cell signaling involved in cell fate commitment [inference]

lateral inhibition

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

cell death [inference]

programmed cell death [inference]

programmed cell death involved in cell development [inference]

retinal cell programmed cell death [inference]

compound eye retinal cell programmed cell death

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oogenesis

follicle cell of egg chamber migration [inference]

border follicle cell migration

cellular developmental process [inference]

cell fate specification

neuron fate specification

cell fate determination [inference]

neuroblast fate determination

programmed cell death involved in cell development [inference]

retinal cell programmed cell death [inference]

compound eye retinal cell programmed cell death

cell differentiation [inference]

neuron differentiation [inference]

photoreceptor cell differentiation [inference]

eye photoreceptor cell differentiation [inference]

compound eye photoreceptor cell differentiation [inference]

stem cell differentiation

cell development [inference]

epithelial cell development [inference]

follicle cell of egg chamber development

germ cell development [inference]

oogenesis

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development [inference]

compound eye photoreceptor development

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

follicle cell of egg chamber migration [inference]

border follicle cell migration

glial cell migration

cell division [inference]

asymmetric cell division

localization of cell [inference]

oocyte localization involved in germarium-derived egg chamber formation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

supramolecular fiber organization [inference]

actin filament organization

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

oogenesis

follicle cell of egg chamber migration [inference]

border follicle cell migration

multicellular organismal reproductive process [inference]

gamete generation [inference]

female gamete generation [inference]

oogenesis

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

imaginal disc pattern formation [inference]

anterior/posterior pattern specification, imaginal disc [inference]

wing disc anterior/posterior pattern formation

dorsal/ventral pattern formation, imaginal disc [inference]

wing disc dorsal/ventral pattern formation

wing disc pattern formation [inference]

anterior/posterior pattern specification [inference]

anterior/posterior pattern specification, imaginal disc [inference]

wing disc anterior/posterior pattern formation

dorsal/ventral pattern formation [inference]

dorsal/ventral pattern formation, imaginal disc [inference]

wing disc dorsal/ventral pattern formation

segmentation [inference]

appendage segmentation [inference]

imaginal disc-derived leg segmentation

stem cell population maintenance [inference]

germ-line stem cell population maintenance

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

follicle cell of egg chamber stalk formation

post-embryonic animal morphogenesis [inference]

post-embryonic appendage morphogenesis [inference]

antennal morphogenesis

animal organ morphogenesis [inference]

chaeta morphogenesis

appendage morphogenesis [inference]

imaginal disc-derived appendage morphogenesis [inference]

post-embryonic appendage morphogenesis [inference]

antennal morphogenesis

anatomical structure development [inference]

tissue development [inference]

mesoderm development

cell development [inference]

epithelial cell development [inference]

follicle cell of egg chamber development

germ cell development [inference]

oogenesis

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development [inference]

compound eye photoreceptor development

animal organ development [inference]

sensory organ development

system development [inference]

peripheral nervous system development

cellular developmental process [inference]

cell fate specification

neuron fate specification

cell fate determination [inference]

neuroblast fate determination

programmed cell death involved in cell development [inference]

retinal cell programmed cell death [inference]

compound eye retinal cell programmed cell death

cell differentiation [inference]

neuron differentiation [inference]

photoreceptor cell differentiation [inference]

eye photoreceptor cell differentiation [inference]

compound eye photoreceptor cell differentiation [inference]

stem cell differentiation

cell development [inference]

epithelial cell development [inference]

follicle cell of egg chamber development

germ cell development [inference]

oogenesis

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development [inference]

compound eye photoreceptor development

maintenance of cell number [inference]

stem cell population maintenance [inference]

germ-line stem cell population maintenance

localization [inference]

localization of cell [inference]

oocyte localization involved in germarium-derived egg chamber formation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

signaling [inference]

cell-cell signaling [inference]

cell-cell signaling involved in cell fate commitment [inference]

lateral inhibition

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of animal organ morphogenesis [inference]

regulation of establishment of planar polarity

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

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GO Term	Evidence Code	PMID
endosome	IDA	19295516
early endosome	IDA	14627723
plasma membrane	IDA	12747835 16459304 16643882 17065551 2185893
plasma membrane	IBA
cell surface	IDA	14627723 20203305

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm [inference]

cell cortex [inference]

cell cortex region [inference]

apical cortex

cytoplasmic region [inference]

cell cortex region [inference]

apical cortex

cell surface

membrane

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome

early endosome

endocytic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome

early endosome

endocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome

early endosome

endocytic vesicle

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GO Term	Evidence Code	PMID
Notch binding	IDA	10504334 12909620 15707586 17923477 2185893
Notch binding	IBA
Notch binding	IPI	15611340 20203305 9872749
calcium ion binding	IEA
protein binding	IPI	15829515

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

lipid binding [inference]

sphingolipid binding [inference]

glycosphingolipid binding

glycolipid binding [inference]

glycosphingolipid binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

carbohydrate derivative binding [inference]

glycolipid binding [inference]

glycosphingolipid binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
calcium ion binding

Displaying **all 4** entries
InterPro
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
EGF-type aspartate/asparagine hydroxylation site

Alliance of Genome Resources

Expression

Displaying **all 10** entries
Location	References
plasma membrane	PMID:12747835 PMID:16459304 PMID:16643882 PMID:17065551 PMID:2185893
cytoplasm	PMID:1383233
cytoplasmic vesicle	PMID:16137928 PMID:17065551
endocytic vesicle	PMID:17028337
endosome	PMID:19295516
intracellular anatomical structure	PMID:12747835
cell surface	PMID:14627723 PMID:20203305
apical cortex	PMID:15760269
membrane	PMID:15611340
early endosome	PMID:14627723

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources
DOID:162	cancer	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	13388	Xenbase:XB-GENE-479210
Xenopus tropicalis	28514	Xenbase:XB-GENE-479210
Xenopus tropicalis	30120	Xenbase:XB-GENE-968497
Xenopus tropicalis	30141	Xenbase:XB-GENE-968497
Xenopus tropicalis	42313	Xenbase:XB-GENE-968497
Xenopus tropicalis	54485	Xenbase:XB-GENE-480902
Xenopus tropicalis	54567	Xenbase:XB-GENE-480902
Xenopus tropicalis	84010	Xenbase:XB-GENE-479210
Homo sapiens	173042	HGNC:2910
Caenorhabditis elegans	178759	WB:WBGene00000168

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements