GlyCosmos Portal

Annotation

Keyword

Cytoplasm
Disulfide bond
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P26572	N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IBA
protein N-linked glycosylation via asparagine	IDA	1702225
viral protein processing	TAS
UDP-N-acetylglucosamine catabolic process	IEA
in utero embryonic development	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

small molecule catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

organic substance catabolic process [inference]

carbohydrate derivative catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

amino sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

phosphorus metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

small molecule metabolic process [inference]

small molecule catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

amino sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

carbohydrate derivative catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

amino sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance catabolic process [inference]

carbohydrate derivative catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

amino sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

phosphorus metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleobase-containing small molecule catabolic process [inference]

nucleotide-sugar catabolic process [inference]

UDP-N-acetylglucosamine catabolic process

viral process [inference]

viral protein processing

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum-Golgi intermediate compartment membrane	TAS
extracellular vesicle	HDA	24769233
membrane	HDA	19946888
Golgi apparatus	IBA
perinuclear region of cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle

extracellular exosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

perinuclear region of cytoplasm

Displaying **all 4** entries
GO Term	Evidence Code	PMID
manganese ion binding	IDA	1702225
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	IBA IDA TAS	1702225
acetylglucosaminyltransferase activity	TAS
protein binding	IPI	30983867

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000131446

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg125

Gene Symbol

MGAT1

Reactions

Displaying 1 entry
Donor	Acceptor	Product	Reference
UDP-GlcNAc	G55220VL	G08520NM	1827260

Displaying **all 3** entries
Donor	Acceptor	Product	Reference
UDP-GlcNAc	G23046QV	G08301LT	17716624
UDP-GlcNAc	G55220VL	G08520NM	1827260
UDP-GlcNAc	G99858XP	G82942ZJ	1827260

Orthologous Gene

Displaying **all 5** entries
Species	Protein	mRNA
Arabidopsis thaliana	NP_195537	NM_119986
Rattus norvegicus	NP_110488	NM_030861
Drosophila melanogaster	NP_525117	NM_080378
Caenorhabditis elegans	NP_509566	NM_077165
Mus musculus	NP_034924	NM_010794

KEGG BRITE Database

Orthology

K00726

Name

alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.101]

References

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05983	2.4.1.101	G55220VL	G08520NM

Rhea

RHEA:11456

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.101

PMID

Disease

Disease Ontology

Displaying entry **71 - 71** of 71 in total

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DO ID	Disease Name	Source
DOID:9970	obesity	DisGeNET

Ortholog

Displaying entries **1 - 10** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	175453	WB:WBGene00001639
Caenorhabditis elegans	181005	WB:WBGene00001637
Caenorhabditis elegans	181160	WB:WBGene00001638
Drosophila melanogaster	37323	FB:FBgn0034521
Latimeria chalumnae	102366347		LATCH12030
Danio rerio	558524	ZFIN:ZDB-GENE-061103-589	DANRE14810
Danio rerio	393649	ZFIN:ZDB-GENE-040426-1515
Astyanax mexicanus	103041286		ASTMX15817
Electrophorus electricus	113590323		ELEEL44725
Salmo salar	106570655		SALSA32294

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

International Collaboration

Acknowledgements