GlyCosmos Portal

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GO Term	Evidence Code	PMID
magnesium ion binding	IEA
pyruvate kinase activity	ISS
pyruvate kinase activity	IDA	38739777
pyruvate kinase activity	IMP	17159148 37792629
pyruvate kinase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

pyruvate kinase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

alkali metal ion binding [inference]

potassium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Pyruvate kinase

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 10** entries
Gene Ontology
ATP binding
catalytic activity
kinase activity
magnesium ion binding
metal ion binding
nucleotide binding
phosphorylation
potassium ion binding
pyruvate kinase activity
transferase activity

Displaying **all 9** entries
InterPro
Pyruvate kinase, C-terminal domain superfamily
Pyruvate kinase, C-terminal
Pyruvate kinase, active site
Pyruvate kinase, barrel
Pyruvate kinase, insert domain superfamily
Pyruvate kinase-like domain superfamily
Pyruvate kinase-like, insert domain superfamily
Pyruvate kinase
Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
cytosol	PMID:14668392
membrane	FB:FBrf0231198

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0014667	disease of metabolism	Alliance of Genome Resources

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	5313	Xenbase:XB-GENE-5918041
Xenopus tropicalis	5315	Xenbase:XB-GENE-485873
Xenopus tropicalis	18746	Xenbase:XB-GENE-485873
Xenopus tropicalis	24651	Xenbase:XB-GENE-5918041
Xenopus tropicalis	25630	Xenbase:XB-GENE-485873
Xenopus tropicalis	42620	Xenbase:XB-GENE-5918041
Xenopus tropicalis	851193	Xenbase:XB-GENE-5918041
Xenopus tropicalis	854529	Xenbase:XB-GENE-5918041

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements