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Autophagy-related 6

Summary

Gene Symbol

Atg6

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

42850

PubChem

42850

Alliance of Genome Resources

FB:FBgn0264325

Annotation

Keyword

Coiled coil
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VCE1	Autophagy protein 6-like

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
glycophagy	IMP	24265594
autophagosome assembly	IBA
autophagy	IEA IMP	23406899
macroautophagy	IGI IMP	18474623 23873149 25882046
cellular response to starvation	IMP	24265594

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy

autophagy of mitochondrion [inference]

mitophagy

macroautophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

autophagy of mitochondrion [inference]

mitophagy

macroautophagy

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cell death [inference]

programmed cell death [inference]

programmed cell death involved in cell development [inference]

larval midgut cell programmed cell death

vesicle-mediated transport [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

autophagy of mitochondrion [inference]

mitophagy

macroautophagy

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

larval midgut cell programmed cell death

cell development [inference]

hemopoiesis

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

late endosome to vacuole transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to stress [inference]

cellular response to starvation

cellular response to nitrogen starvation

process utilizing autophagic mechanism [inference]

autophagy

autophagy of mitochondrion [inference]

mitophagy

macroautophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

autophagy of mitochondrion [inference]

mitophagy

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

organelle disassembly [inference]

autophagy of mitochondrion [inference]

mitophagy

cellular component disassembly [inference]

organelle disassembly [inference]

autophagy of mitochondrion [inference]

mitophagy

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

export from cell [inference]

secretion by cell [inference]

protein secretion

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

anatomical structure development [inference]

cell development [inference]

hemopoiesis

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

larval midgut cell programmed cell death

cell development [inference]

hemopoiesis

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

response to oxidative stress

cellular response to stress [inference]

cellular response to starvation

cellular response to nitrogen starvation

response to starvation [inference]

cellular response to starvation

cellular response to nitrogen starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

response to starvation [inference]

cellular response to starvation

cellular response to nitrogen starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

defense response to other organism [inference]

defense response to bacterium [inference]

defense response to Gram-negative bacterium

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to nitrogen starvation

cellular response to nitrogen levels [inference]

cellular response to nitrogen starvation

cellular response to stress [inference]

cellular response to starvation

cellular response to nitrogen starvation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

secretion [inference]

secretion by cell [inference]

protein secretion

intracellular transport [inference]

vacuolar transport [inference]

late endosome to vacuole transport

organic substance transport [inference]

protein transport [inference]

protein secretion

nitrogen compound transport [inference]

protein transport [inference]

protein secretion

import into cell [inference]

endocytosis

export from cell [inference]

secretion by cell [inference]

protein secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

late endosome to vacuole transport

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

late endosome to vacuole transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of defense response [inference]

negative regulation of innate immune response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response

negative regulation of defense response [inference]

negative regulation of innate immune response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response

Displaying **all 3** entries
GO Term	Evidence Code	PMID
phosphatidylinositol 3-kinase complex, class III, type I	IBA IDA	18474623
phosphatidylinositol 3-kinase complex, class III, type II	IBA
phagophore assembly site	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

phosphatidylinositol 3-kinase complex [inference]

phosphatidylinositol 3-kinase complex, class III [inference]

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

phosphatidylinositol 3-kinase complex [inference]

phosphatidylinositol 3-kinase complex, class III [inference]

cellular anatomical entity [inference]

phagophore assembly site

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein-macromolecule adaptor activity	IBA
phosphatidylinositol 3-kinase binding	IBA
small GTPase binding	IDA	32248620

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

phosphatidylinositol 3-kinase binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
phosphatidylinositol 3-kinase complex, class III, type I	PMID:18474623

Disease

Disease Ontology

Displaying entries **1 - 10** of 39 in total

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DO ID	Disease Name	Source
DOID:0080322	polycystic kidney disease	Alliance of Genome Resources
DOID:0080546	non-alcoholic fatty liver	Alliance of Genome Resources
DOID:0080855	Parkinsonism	Alliance of Genome Resources
DOID:0080998	acute necrotizing pancreatitis	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:11984	hypertrophic cardiomyopathy	Alliance of Genome Resources
DOID:12010	anterior ischemic optic neuropathy	Alliance of Genome Resources
DOID:1440	Machado-Joseph disease	Alliance of Genome Resources
DOID:1596	depressive disorder	Alliance of Genome Resources

GlyTouCan

GlyComb

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UniCarb-DR

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Acknowledgements