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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
marker of proliferation Ki-67
Summary
- Gene Symbol
-
- MKI67
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Cell cycle
- Chromosome
- DNA-binding
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P46013 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of chromosome segregation | ||
| cell population proliferation | ||
| regulation of chromatin organization | ||
| regulation of mitotic nuclear division |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| condensed chromosome | ||
| nucleoplasm | ||
| nuclear body | ||
| nucleus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| DNA binding | ||
| ATP binding | ||
| RNA binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Antigen KI-67
- Functional Category
-
- G: Carbohydrate transport and metabolism
- I: Lipid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| regulation of chromosome segregation |
| regulation of mitotic nuclear division |
| InterPro |
|---|
| Forkhead-associated (FHA) domain |
| SMAD/FHA domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050745 | diffuse large B-cell lymphoma | |
| DOID:0080178 | mucositis | |
| DOID:0081267 | graft-versus-host disease | |
| DOID:10286 | prostate carcinoma | |
| DOID:10534 | stomach cancer | |
| DOID:11054 | urinary bladder cancer | |
| DOID:1227 | neutropenia | |
| DOID:127 | leiomyoma | |
| DOID:1324 | lung cancer | |
| DOID:13949 | interstitial cystitis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 17345 | MGI:106035 | MOUSE56157 | ||
| 291234 | RGD:1305476 | RATNO16345 | ||
| 450866 | 9598_0:002ac0 | PANTR01802 | ||
| 513220 | BOVIN21758 | |||
| 564521 | ZFIN:ZDB-GENE-030131-9771 | |||
| 697883 | MACMU45795 | |||
| 779458 | Xenbase:XB-GENE-6457930 | |||
| 100126001 | Xenbase:XB-GENE-17330955 | |||
| 100189585 | Xenbase:XB-GENE-6252898 | |||
| 100411224 | CALJA08083 |
