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beta-4-galactosyltransferase 7

Summary

Gene Symbol

beta4GalT7

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

42991

KEGG Gene ID

dme:Dmel_CG11780

PubChem

42991

Alliance of Genome Resources

FB:FBgn0039258

Annotation

Keyword

3D-structure
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Nucleotide-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VBZ9	Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I Xylosylprotein beta 4-galactosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein glycosylation
proteoglycan biosynthetic process	IBA IDA ISS	12215432 12244071 12590131
N-glycan processing	IDA	21501638
carbohydrate metabolic process	IEA
glycosylation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

N-glycan processing

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

N-glycan processing

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

protein modification process [inference]

protein glycosylation

glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

N-glycan processing

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

N-glycan processing

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

N-glycan processing

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

protein modification process [inference]

protein glycosylation

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	ISS	12590131
Golgi apparatus	IBA IDA	12244071
Golgi membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
xylosylprotein 4-beta-galactosyltransferase activity	IBA IDA ISS	12215432 12244071 12590131
metal ion binding	ISS	12590131
nucleotide binding
glycosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

UDP-galactosyltransferase activity [inference]

xylosylprotein 4-beta-galactosyltransferase activity

hexosyltransferase activity [inference]

galactosyltransferase activity [inference]

UDP-galactosyltransferase activity [inference]

xylosylprotein 4-beta-galactosyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

xylosylprotein 4-beta-galactosyltransferase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Beta-1,4-galactosyltransferase 7

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
glycosylation
proteoglycan biosynthetic process
transferase activity
xylosylprotein 4-beta-galactosyltransferase activity

Displaying **all 4** entries
InterPro
Beta-1,4-galactosyltransferase
Galactosyltransferase, C-terminal
Galactosyltransferase, N-terminal
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K00733

Name

xylosylprotein 4-beta-galactosyltransferase [EC:2.4.1.133]

References

10438455

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05926	2.4.1.133	G16579HJ	G78098IA

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
Golgi apparatus	PMID:12244071
membrane	FB:FBrf0231198

Rhea

RHEA:15297

UDP-α-D-galactose

H⁺ + UDP

Enzyme

2.4.1.133

PMID

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080738	Ehlers-Danlos syndrome spondylodysplastic type 1	Alliance of Genome Resources
DOID:13359	Ehlers-Danlos syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 43 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	11285		HGNC:930
Caenorhabditis elegans	176382		WB:WBGene00005021
Mus musculus	218271		MGI:2384987
Rattus norvegicus	364675		RGD:1309214
Danio rerio	445022		ZFIN:ZDB-GENE-040727-3
Drosophila pseudoobscura	4801371	7237_1:00046b
Drosophila ananassae	6507960	7217_1:000754
Drosophila yakuba	6538614	7245_1:002c57
Drosophila erecta	6554264	7220_0:000693
Drosophila grimshawi	6570736	7222_1:001a23

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements