matrix metallopeptidase 2

Summary
Gene Symbol
  • MMP2
Organism
Homo sapiens (human)
NCBI Gene
4313
PubChem
4313
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Angiogenesis
  • Autocatalytic cleavage
  • Calcium
  • Collagen degradation
  • Cytoplasm
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Membrane
  • Metal-binding
  • Metalloprotease
  • Mitochondrion
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Signal
  • Zinc
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
P08253
  • 72 kDa gelatinase
  • Gelatinase A
  • Matrix metalloproteinase-2
  • TBE-1
Gene Ontology (GO)
Displaying entries 1 - 5 of 47 in total
GO Term Evidence Code PMID
angiogenesis
ovarian follicle development
ovulation from ovarian follicle
luteinization
response to hypoxia
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
metallopeptidase
Functional Category
  • M: Cell wall/membrane/envelope biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying entries 1 - 10 of 11 in total
DO ID Disease Name Source
DOID:0002116 pterygium
DOID:10763 hypertension
DOID:10941 intracranial aneurysm
DOID:11830 myopia
DOID:13375 temporal arteritis
DOID:1727 retinal vein occlusion
DOID:2349 arteriosclerosis
DOID:2738 pseudoxanthoma elasticum
DOID:3407 carotid artery disease
DOID:4448 macular degeneration

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025