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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
lysosomal enzyme receptor protein
Summary
- Gene Symbol
-
- Lerp
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Disulfide bond
- Proteomics identification
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| B7Z0Q8 |
|
| Q8IMR1 |
|
| A0A0B4KH68 |
|
| Q8IMR0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lysosomal transport | ||
| positive regulation of autophagy | ||
| post-Golgi vesicle-mediated transport |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| late endosome | ||
| clathrin-coated vesicle | ||
| plasma membrane | ||
| trans-Golgi network | ||
| perinuclear region of cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| insulin-like growth factor binding | ||
| mannose binding | ||
| signaling receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Cation-independent mannose-6-phosphate receptor
- Functional Category
-
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| MRH domain |
| Mannose-6-phosphate receptor binding domain superfamily |
| Mannose-6-phosphate receptor |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060060 | non-Hodgkin lymphoma | |
| DOID:1520 | colon carcinoma | |
| DOID:2154 | nephroblastoma | |
| DOID:332 | amyotrophic lateral sclerosis | |
| DOID:3459 | breast carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:8719 | in situ carcinoma | |
| DOID:8791 | breast carcinoma in situ | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 3482 | HGNC:5467 | |||
| 16004 | MGI:96435 | |||
| 25151 | RGD:2871 | |||
| 496491 | Xenbase:XB-GENE-480957 | |||
| 557061 | ZFIN:ZDB-GENE-041014-300 | |||
| 4800748 | 7237_0:001bdb | |||
| 6501338 | 7217_0:000cb3 | |||
| 6538351 | 7245_1:002f6a | |||
| 6555255 | 7220_1:0006d9 | |||
| 6569894 | 7222_1:0016e9 |
