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N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

Summary

Gene Symbol

Gnptab

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

432486

PubChem

432486

Alliance of Genome Resources

MGI:3643902

Annotation

Keyword

Alternative splicing
Calcium
Disulfide bond
Glycoprotein
Golgi apparatus
Metal-binding
Reference proteome
Repeat
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q69ZN6	GlcNAc-1-phosphotransferase subunits alpha/beta Stealth protein GNPTAB UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
carbohydrate phosphorylation	IBA IMP ISO	17652091

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing [inference]

N-glycan processing to lysosome

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

carbohydrate phosphorylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate phosphorylation

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing [inference]

N-glycan processing to lysosome

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate phosphorylation

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing [inference]

N-glycan processing to lysosome

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing [inference]

N-glycan processing to lysosome

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

N-glycan processing [inference]

N-glycan processing to lysosome

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

carbohydrate phosphorylation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

secretion of lysosomal enzymes

establishment of protein localization to extracellular region [inference]

protein secretion

secretion of lysosomal enzymes

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

secretion of lysosomal enzymes

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

export from cell [inference]

secretion by cell [inference]

protein secretion

secretion of lysosomal enzymes

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

secretion of lysosomal enzymes

establishment of protein localization to extracellular region [inference]

protein secretion

secretion of lysosomal enzymes

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

secretion of lysosomal enzymes

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

protein secretion

secretion of lysosomal enzymes

organic substance transport [inference]

protein transport [inference]

protein secretion

secretion of lysosomal enzymes

nitrogen compound transport [inference]

protein transport [inference]

protein secretion

secretion of lysosomal enzymes

export from cell [inference]

secretion by cell [inference]

protein secretion

secretion of lysosomal enzymes

establishment of protein localization [inference]

protein transport [inference]

protein secretion

secretion of lysosomal enzymes

establishment of protein localization to extracellular region [inference]

protein secretion

secretion of lysosomal enzymes

establishment of localization in cell

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

secretion of lysosomal enzymes

establishment of protein localization to extracellular region [inference]

protein secretion

secretion of lysosomal enzymes

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

secretion of lysosomal enzymes

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA
Golgi apparatus	IBA ISO
Golgi membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
transferase activity, transferring phosphorus-containing groups	IEA
transferase activity	IEA
calcium ion binding	IEA
metal ion binding	IEA
UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity	IBA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

transferase activity, transferring phosphorus-containing groups

phosphotransferase activity, for other substituted phosphate groups [inference]

UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080070	mucolipidosis II alpha/beta	Alliance of Genome Resources
DOID:0080071	mucolipidosis III alpha/beta	Alliance of Genome Resources
DOID:0080488	mucolipidosis	Alliance of Genome Resources

Ortholog

Displaying entries **71 - 80** of 80 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Chelonoidis abingdonii	116825717		CHEAB08342
Pteropus vampyrus	105310616		PTEVA14280
Echeneis naucrates	115036759		ECHNA42429
Salarias fasciatus	115404110		SALFA09134
Propithecus coquereli	105815137		PROCO23960
Cyprinus carpio carpio	109052697		CYPCA32522
Cyprinus carpio carpio	109071546		CYPCA62168
Corvus moneduloides	116442473		CORMO19775
Carlito syrichta	103258830		CARSF15315
Strigops habroptila	115604748		STRHB22404

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 19, 2024