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Cadherin 99C

Summary

Gene Symbol

Cad99C

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

43528

PubChem

43528

Alliance of Genome Resources

FB:FBgn0039709

Annotation

Keyword

Calcium
Cell membrane
Cell projection
Endosome
Glycoprotein
Immunity
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VAF5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 14** of 14 in total

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GO Term	Evidence Code	PMID
apical protein localization	IMP	24718992
mucosal immune response	IGI IMP	25639794
chorion-containing eggshell formation	IMP	16260500
tube morphogenesis	IMP	24718992

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cellular process involved in reproduction in multicellular organism [inference]

egg coat formation [inference]

vitelline membrane formation [inference]

vitelline membrane formation involved in chorion-containing eggshell formation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

apical protein localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

vitelline membrane formation [inference]

vitelline membrane formation involved in chorion-containing eggshell formation

extracellular matrix assembly [inference]

vitelline membrane formation [inference]

vitelline membrane formation involved in chorion-containing eggshell formation

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

microvillus organization [inference]

follicle cell microvillus organization

regulation of cellular component size [inference]

regulation of cell size [inference]

regulation of follicle cell microvillus length

regulation of cell projection size [inference]

regulation of microvillus length [inference]

regulation of follicle cell microvillus length

extracellular structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix assembly [inference]

vitelline membrane formation [inference]

vitelline membrane formation involved in chorion-containing eggshell formation

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix assembly [inference]

vitelline membrane formation [inference]

vitelline membrane formation involved in chorion-containing eggshell formation

reproductive process [inference]

developmental process involved in reproduction [inference]

eggshell formation [inference]

chorion-containing eggshell formation

vitelline membrane formation [inference]

vitelline membrane formation involved in chorion-containing eggshell formation

cellular process involved in reproduction in multicellular organism [inference]

egg coat formation [inference]

vitelline membrane formation [inference]

vitelline membrane formation involved in chorion-containing eggshell formation

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

developmental process [inference]

developmental process involved in reproduction [inference]

eggshell formation [inference]

chorion-containing eggshell formation

vitelline membrane formation [inference]

vitelline membrane formation involved in chorion-containing eggshell formation

anatomical structure morphogenesis [inference]

tube morphogenesis

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

vitelline membrane formation [inference]

vitelline membrane formation involved in chorion-containing eggshell formation

eggshell formation [inference]

chorion-containing eggshell formation

response to stimulus [inference]

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

apical protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

apical protein localization

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of clathrin-dependent endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of clathrin-dependent endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of microvillus organization [inference]

regulation of follicle cell microvillus organization [inference]

regulation of follicle cell microvillus length

regulation of microvillus length [inference]

regulation of follicle cell microvillus length

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of clathrin-dependent endocytosis [inference]

positive regulation of clathrin-dependent endocytosis

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

regulation of follicle cell microvillus length

regulation of cell projection size [inference]

regulation of microvillus length [inference]

regulation of follicle cell microvillus length

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
microvillus	IDA	16260500 16507588
apical plasma membrane	IDA	16507588
plasma membrane	IEA ISS NAS	10908592 11162110
endosome	IDA	25639794
microvillus membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
myosin binding	IPI	25236597
calcium ion binding	IEA ISM	11162110

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

myosin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Uncharacterized protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 3** entries
InterPro
Cadherin conserved site
Cadherin-like superfamily
Cadherin-like

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
brush border membrane	PMID:25639794
microvillus	PMID:16260500 PMID:16507588
endosome	PMID:25639794
apical plasma membrane	PMID:16507588

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0110481	autosomal recessive nonsyndromic deafness 23	Alliance of Genome Resources
DOID:0110831	Usher syndrome type 1D	Alliance of Genome Resources
DOID:0110832	Usher syndrome type 1F	Alliance of Genome Resources