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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
myelin protein zero
Summary
- Gene Symbol
-
- MPZ
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Charcot-Marie-Tooth disease
- Deafness
- Dejerine-Sottas syndrome
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Neurodegeneration
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P25189 |
|
| A0A5F9ZI26 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| myelination | ||
| cell-cell adhesion via plasma-membrane adhesion molecules | ||
| cell aggregation | ||
| chemical synaptic transmission |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| myelin sheath | ||
| synapse |
| GO Term | Evidence Code | PMID |
|---|---|---|
| structural molecule activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- myelin protein P0
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| myelination |
| InterPro |
|---|
| Immunoglobulin V-set domain |
| Immunoglobulin-like domain superfamily |
| Immunoglobulin-like domain |
| Immunoglobulin-like fold |
| Myelin P0 protein-related |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050540 | Charcot-Marie-Tooth disease type 3 | |
| DOID:0090111 | PCWH syndrome | |
| DOID:0110152 | Charcot-Marie-Tooth disease type 1B | |
| DOID:0110157 | Charcot-Marie-Tooth disease type 2J | |
| DOID:0110158 | Charcot-Marie-Tooth disease type 2I | |
| DOID:0110200 | Charcot-Marie-Tooth disease dominant intermediate D | |
| DOID:10595 | Charcot-Marie-Tooth disease | |
| DOID:11446 | sciatic neuropathy | |
| DOID:870 | neuropathy | |
| DOID:9743 | diabetic neuropathy |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 17528 | MGI:103177 | MOUSE30119 | ||
| 24564 | RGD:3109 | |||
| 114417 | ZFIN:ZDB-GENE-010724-4 | DANRE28389 | ||
| 488654 | CANLF14403 | |||
| 539462 | BOVIN25521 | |||
| 719969 | MACMU24152 | |||
| 747431 | 9598_0:000800 | PANTR22824 | ||
| 780198 | Xenbase:XB-GENE-876969 | |||
| 100034024 | HORSE35708 | |||
| 100037196 | Xenbase:XB-GENE-876975 |
