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LARGE xylosyl- and glucuronyltransferase 1

Summary

Gene Symbol

large1

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

446213

KEGG Gene ID

dre:446213

PubChem

446213

Alliance of Genome Resources

ZFIN:ZDB-GENE-061204-1

Annotation

Keyword

Coiled coil
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Multifunctional enzyme
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B3DFM4
F1RE53
Q66PG2	Acetylglucosaminyltransferase-like 1A Glycosyltransferase-like protein LARGE xylosyl- and glucuronyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
skeletal muscle tissue regeneration	ISS
metabolic process	IEA
skeletal muscle organ development	ISS
protein glycosylation	ISS
protein O-linked mannosylation	IBA ISS

GO Hierarchy

biological process

metabolic process

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

tissue regeneration [inference]

skeletal muscle tissue regeneration

animal organ development [inference]

muscle organ development [inference]

skeletal muscle organ development

muscle structure development [inference]

muscle organ development [inference]

skeletal muscle organ development

growth [inference]

developmental growth [inference]

tissue regeneration [inference]

skeletal muscle tissue regeneration

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA
Golgi apparatus	IBA IEA ISS	15958417
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
catalytic activity	IEA
glycosyltransferase activity	IEA
hexosyltransferase activity	IEA ISS
transferase activity	IEA
manganese ion binding	ISS

GO Hierarchy

molecular function

catalytic activity

transferase activity

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity

glucuronosyltransferase activity

pentosyltransferase activity

xylosyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K09668

Name

glycosyltransferase-like protein LARGE [EC:2.4.2.- 2.4.1.-]

References

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050588	muscular dystrophy-dystroglycanopathy type B1	Alliance of Genome Resources
DOID:0110637	muscular dystrophy-dystroglycanopathy type B6	Alliance of Genome Resources
DOID:0111242	congenital muscular dystrophy-dystroglycanopathy type A6	Alliance of Genome Resources
DOID:11727	facioscapulohumeral muscular dystrophy	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP011855
Gene Name: like-glycosyltransferase

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	187206	WB:WBGene00010716
Callorhinchus milii	103181844		CALMI23854
Latimeria chalumnae	102357936		LATCH18608
Astyanax mexicanus	103045143		ASTMX14437
Electrophorus electricus	113573532		ELEEL13090
Electrophorus electricus	113573576		ELEEL13088
Oryzias latipes	101164859		ORYLA10880
Oreochromis niloticus	100696542		ORENI17896
Xenopus tropicalis	100498555	Xenbase:XB-GENE-6250446
Chrysemys picta bellii	101949235		CHRPI06580

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements