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LARGE xylosyl- and glucuronyltransferase 1

Summary

Gene Symbol

large1

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

446213

KEGG Gene ID

dre:446213

PubChem

446213

Alliance of Genome Resources

ZFIN:ZDB-GENE-061204-1

Annotation

Keyword

Coiled coil
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Multifunctional enzyme
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B3DFM4
F1RE53
Q66PG2	Acetylglucosaminyltransferase-like 1A Glycosyltransferase-like protein LARGE xylosyl- and glucuronyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
skeletal muscle tissue regeneration	ISS
metabolic process	IEA
skeletal muscle organ development	ISS
protein glycosylation	ISS
protein O-linked mannosylation	IBA ISS

GO Hierarchy

biological process

metabolic process

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

mannosylation [inference]

protein mannosylation [inference]

protein O-linked mannosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

macromolecule glycosylation [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

protein O-linked glycosylation [inference]

protein O-linked mannosylation

protein mannosylation [inference]

protein O-linked mannosylation

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

tissue regeneration [inference]

skeletal muscle tissue regeneration

animal organ development [inference]

muscle organ development [inference]

skeletal muscle organ development

muscle structure development [inference]

muscle organ development [inference]

skeletal muscle organ development

growth [inference]

developmental growth [inference]

tissue regeneration [inference]

skeletal muscle tissue regeneration

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA
Golgi apparatus	IBA IEA ISS	15958417
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
pentosyltransferase activity	IEA
metal ion binding	IEA
xylosyltransferase activity	IBA ISS
glucuronosyltransferase activity	IBA ISS

GO Hierarchy

molecular function

catalytic activity

transferase activity

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity

glucuronosyltransferase activity

pentosyltransferase activity

xylosyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K09668

Name

glycosyltransferase-like protein LARGE [EC:2.4.2.- 2.4.1.-]

References

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050588	muscular dystrophy-dystroglycanopathy type B1	Alliance of Genome Resources
DOID:0110637	muscular dystrophy-dystroglycanopathy type B6	Alliance of Genome Resources
DOID:0111242	congenital muscular dystrophy-dystroglycanopathy type A6	Alliance of Genome Resources
DOID:11727	facioscapulohumeral muscular dystrophy	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP011855
Gene Name: like-glycosyltransferase

Ortholog

Displaying entries **51 - 60** of 77 in total

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Species	Gene ID	Orthologous MAtrix
Anolis carolinensis	100560778	ANOCA06886
Vombatus ursinus	114051325	VOMUR17055
Microcebus murinus	105864360	MICMU13093
Otolemur garnettii	100965890	OTOGA17465
Takifugu rubripes	101061367	TAKRU18437
Aotus nancymaae	105730290	AOTNA34429
Saimiri boliviensis boliviensis	101040901	SAIBB21223
Jaculus jaculus	101607689	JACJA01336
Myotis lucifugus	102423999	MYOLU07408
Rhinolophus ferrumequinum	117028586	RHIFE09423

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

Tools

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Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements